Predictors of physical activity levels in children and adolescents with cerebral palsy: Clinical cohort study protocol

Christina Esmann Fonvig*, Jens Troelsen, Ulrike Dunkhase-Heinl, Jens Martin Lauritsen, Anders Holsgaard-Larsen


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INTRODUCTION: Children and adolescents with cerebral palsy may be trapped in a vicious circle of low physical fitness, resulting in deconditioning that causes a further decrease in physical activity (PA), a lower quality of life and an increased risk of developing non-communicable diseases. Therefore, establishing a healthy and active lifestyle during childhood is even more important for individuals with a disability. However, the factors that influence habitual PA in children and adolescents with cerebral palsy remain unknown.The present protocol outlines a prospective cohort study with the aim of investigating potential predictors of habitual PA in children and adolescents with cerebral palsy in order to provide evidence for optimising PA levels and associated overall health.

METHODS AND ANALYSIS: This prospective cohort study will enrol participants with cerebral palsy between the ages of 8 and 15 years at Gross Motor Function Classification System levels I-III. Using a modified version of the International Classification of Functioning, Disability and Health model as a conceptual analytical framework, the analysis will be divided into six components and will provide predictors for habitual PA measured by accelerometry. The potential predictive variables are registry data on physical function (Danish Cerebral Palsy Follow-Up Programme); validated proxy-reported questionnaires on quality of life (Paediatric Quality of Life Inventory), overall health, pain and participation in daily activities (Paediatric Outcomes Data Collection Instrument) and supplementary questions regarding sleep, screen time and socioeconomic status.

ETHICS AND DISSEMINATION: The project is approved by the Danish Data Protection Agency (19/16396) and has been declared not notifiable by the Regional Committee on Health Research Ethics, cf. Committee Act Art. 14, paragraph 1 (S-20192000-23). The study results will be published in international peer-reviewed journals, presented at international conferences, and published in a PhD dissertation.


TidsskriftBMJ Open
Udgave nummer9
Antal sider10
StatusUdgivet - 21. sep. 2021

Bibliografisk note

Funding Information:
Funding The project is funded by the Elsass Foundation, A.J.Andersen & Hustrus Fond, the Region of Southern Denmark, Familien Hede Nielsens Fond, Dagmar Marshalls Fond and A.P. Moellers Fond.


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