Population surveys in Greenland 1993-2009: Temporal trend of PCBs and pesticides in the general Inuit population by age and urbanisation

Peter Bjerregaard, Henning Sloth Pedersen, Nina O Nielsen, Eric Dewailly

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

The purpose of the study was to analyse temporal trends (1993-2009) of the concentrations of organochlorine contaminants (14 congeners of polychlorinated biphenyls (PCB) and 11 pesticides) in the blood of Greenland Inuit according to age and urbanisation. Statistical determinants for the contaminant concentrations included (for PCB congener 153) age (Δr(2)=0.35), marine diet (Δr(2)=0.10), smoking (Δr(2)=0.02), and sex (Δr(2)=0.01) with comparable results for other organochlorine contaminants. After adjustment for age, diet, smoking, and sex a significant decreasing trend was present for all contaminants ranging from 41% for mirex to 56% for hexachlorobenzene. The temporal trend was most pronounced among participants below the age of 65years. The decrease started later in villages than in towns. The decrease was present in all age groups and in the capital, other towns, and villages. The decrease is probably due to a combination of reduced concentrations of the contaminants in the wildlife and a slight temporal reduction in the consumption of marine mammals. The significant downwards trend of legacy POPs shows that the legislation works but it must be kept in mind that according to the cumulated scientific evidence there are a multitude of non-regulated persistent organic contaminants in the diet as well as high levels of methylmercury.
OriginalsprogEngelsk
TidsskriftScience of the Total Environment
Vol/bind454-455C
Sider (fra-til)283-288
Antal sider6
ISSN0048-9697
DOI
StatusUdgivet - 2. apr. 2013

Fingeraftryk

Polychlorinated Biphenyls
Pesticides
Polychlorinated biphenyls
PCB
urbanization
pesticide
Impurities
pollutant
Nutrition
diet
smoking
organochlorine
village
Mirex
Hexachlorobenzene
Mammals
hexachlorobenzene
marine mammal
methylmercury
trend

Citer dette

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title = "Population surveys in Greenland 1993-2009: Temporal trend of PCBs and pesticides in the general Inuit population by age and urbanisation",
abstract = "The purpose of the study was to analyse temporal trends (1993-2009) of the concentrations of organochlorine contaminants (14 congeners of polychlorinated biphenyls (PCB) and 11 pesticides) in the blood of Greenland Inuit according to age and urbanisation. Statistical determinants for the contaminant concentrations included (for PCB congener 153) age (Δr(2)=0.35), marine diet (Δr(2)=0.10), smoking (Δr(2)=0.02), and sex (Δr(2)=0.01) with comparable results for other organochlorine contaminants. After adjustment for age, diet, smoking, and sex a significant decreasing trend was present for all contaminants ranging from 41{\%} for mirex to 56{\%} for hexachlorobenzene. The temporal trend was most pronounced among participants below the age of 65years. The decrease started later in villages than in towns. The decrease was present in all age groups and in the capital, other towns, and villages. The decrease is probably due to a combination of reduced concentrations of the contaminants in the wildlife and a slight temporal reduction in the consumption of marine mammals. The significant downwards trend of legacy POPs shows that the legislation works but it must be kept in mind that according to the cumulated scientific evidence there are a multitude of non-regulated persistent organic contaminants in the diet as well as high levels of methylmercury.",
author = "Peter Bjerregaard and Pedersen, {Henning Sloth} and Nielsen, {Nina O} and Eric Dewailly",
note = "Copyright {\circledC} 2013 Elsevier B.V. All rights reserved.",
year = "2013",
month = "4",
day = "2",
doi = "10.1016/j.scitotenv.2013.03.031",
language = "English",
volume = "454-455C",
pages = "283--288",
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Population surveys in Greenland 1993-2009 : Temporal trend of PCBs and pesticides in the general Inuit population by age and urbanisation. / Bjerregaard, Peter; Pedersen, Henning Sloth; Nielsen, Nina O; Dewailly, Eric.

I: Science of the Total Environment, Bind 454-455C, 02.04.2013, s. 283-288.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Population surveys in Greenland 1993-2009

T2 - Temporal trend of PCBs and pesticides in the general Inuit population by age and urbanisation

AU - Bjerregaard, Peter

AU - Pedersen, Henning Sloth

AU - Nielsen, Nina O

AU - Dewailly, Eric

N1 - Copyright © 2013 Elsevier B.V. All rights reserved.

PY - 2013/4/2

Y1 - 2013/4/2

N2 - The purpose of the study was to analyse temporal trends (1993-2009) of the concentrations of organochlorine contaminants (14 congeners of polychlorinated biphenyls (PCB) and 11 pesticides) in the blood of Greenland Inuit according to age and urbanisation. Statistical determinants for the contaminant concentrations included (for PCB congener 153) age (Δr(2)=0.35), marine diet (Δr(2)=0.10), smoking (Δr(2)=0.02), and sex (Δr(2)=0.01) with comparable results for other organochlorine contaminants. After adjustment for age, diet, smoking, and sex a significant decreasing trend was present for all contaminants ranging from 41% for mirex to 56% for hexachlorobenzene. The temporal trend was most pronounced among participants below the age of 65years. The decrease started later in villages than in towns. The decrease was present in all age groups and in the capital, other towns, and villages. The decrease is probably due to a combination of reduced concentrations of the contaminants in the wildlife and a slight temporal reduction in the consumption of marine mammals. The significant downwards trend of legacy POPs shows that the legislation works but it must be kept in mind that according to the cumulated scientific evidence there are a multitude of non-regulated persistent organic contaminants in the diet as well as high levels of methylmercury.

AB - The purpose of the study was to analyse temporal trends (1993-2009) of the concentrations of organochlorine contaminants (14 congeners of polychlorinated biphenyls (PCB) and 11 pesticides) in the blood of Greenland Inuit according to age and urbanisation. Statistical determinants for the contaminant concentrations included (for PCB congener 153) age (Δr(2)=0.35), marine diet (Δr(2)=0.10), smoking (Δr(2)=0.02), and sex (Δr(2)=0.01) with comparable results for other organochlorine contaminants. After adjustment for age, diet, smoking, and sex a significant decreasing trend was present for all contaminants ranging from 41% for mirex to 56% for hexachlorobenzene. The temporal trend was most pronounced among participants below the age of 65years. The decrease started later in villages than in towns. The decrease was present in all age groups and in the capital, other towns, and villages. The decrease is probably due to a combination of reduced concentrations of the contaminants in the wildlife and a slight temporal reduction in the consumption of marine mammals. The significant downwards trend of legacy POPs shows that the legislation works but it must be kept in mind that according to the cumulated scientific evidence there are a multitude of non-regulated persistent organic contaminants in the diet as well as high levels of methylmercury.

U2 - 10.1016/j.scitotenv.2013.03.031

DO - 10.1016/j.scitotenv.2013.03.031

M3 - Journal article

C2 - 23562682

VL - 454-455C

SP - 283

EP - 288

JO - Science of the Total Environment

JF - Science of the Total Environment

SN - 0048-9697

ER -