Polymer photonic crystal dye lasers as optofluidic cell sensors

Mads Brøkner Christiansen, Joanna M. Lopacinska, Mogens Havsteen Jakobsen, Niels Asger Mortensen, Hans Martin Dufva, Anders Kristensen

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Abstrakt

Dye doped hybrid polymer lasers are implemented as label free evanescent field biosensors for detection of cells. It is demonstrated that although the coverage is irregular and the cells extend over several lattice constants, the emission wavelength depends linearly on the fraction of the surface covered by the HeLa cells used as model system. Design parameters relating to photonic crystal sensing of large objects are identified and discussed. The lasers are chemically modified to bind cells and molecules with flexible UV activated linker molecules.
OriginalsprogEngelsk
TidsskriftOptics Express
Vol/bind17
Udgave nummer4
Sider (fra-til)2722-2730
ISSN1094-4087
DOI
StatusUdgivet - 2009
Udgivet eksterntJa

Bibliografisk note

This paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the OSA website - please follow the DOI. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.

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