Pneumocystis carinii pneumonia in AIDS patients

clinical course in relation to the parasite number found in routine specimens obtained by fiberoptic bronchoscopy

Marianne Orholm, T L Nielsen, W Holten-Andersen, Anne Lester, H J Kolmos

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

The aim of this study was to evaluate whether the amount of Pneumocystis carinii organisms found at fiberoptic bronchoscopy (FB) performed on HIV-positive patients correlated to the character of the P. carinii pneumonia (PCP). A consecutive series of 105 patients presented with 131 episodes of pulmonary symptoms requiring FB, and in 75 of these episodes a diagnosis of PCP was made. Specimens were stained with Giemsa and methenamine silver nitrate and the number of parasites found was given as: numerous, many, few or none. The following signs and symptoms were registered: cough, dyspnoea, fever, loss of weight, chest radiograph, haemoglobin, WBC, CD4 cell count, PO2 and HIV p24 antigen. The PCP was characterized by the clinical course: mild, moderate, severe, and by the outcome: pulmonary healthy, pulmonary insufficiency and death. No correlations between the number of P. carinii organisms and the clinical course or outcome of the PCP, the symptoms before the FB or the paraclinical examinations were found. In conclusion, the routinely obtained quantitative results of the microbiological examinations of material from the lungs were not correlated to the severity of the PCP.

OriginalsprogEngelsk
TidsskriftScandinavian Journal of Infectious Diseases
Vol/bind24
Udgave nummer3
Sider (fra-til)301-7
Antal sider7
ISSN0036-5548
StatusUdgivet - 1992

Fingeraftryk

Pneumocystis Pneumonia
Parasites
Acquired Immunodeficiency Syndrome
Pneumocystis carinii
Lung
HIV Core Protein p24
Methenamine
Silver Nitrate
Cough
HIV

Citer dette

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title = "Pneumocystis carinii pneumonia in AIDS patients: clinical course in relation to the parasite number found in routine specimens obtained by fiberoptic bronchoscopy",
abstract = "The aim of this study was to evaluate whether the amount of Pneumocystis carinii organisms found at fiberoptic bronchoscopy (FB) performed on HIV-positive patients correlated to the character of the P. carinii pneumonia (PCP). A consecutive series of 105 patients presented with 131 episodes of pulmonary symptoms requiring FB, and in 75 of these episodes a diagnosis of PCP was made. Specimens were stained with Giemsa and methenamine silver nitrate and the number of parasites found was given as: numerous, many, few or none. The following signs and symptoms were registered: cough, dyspnoea, fever, loss of weight, chest radiograph, haemoglobin, WBC, CD4 cell count, PO2 and HIV p24 antigen. The PCP was characterized by the clinical course: mild, moderate, severe, and by the outcome: pulmonary healthy, pulmonary insufficiency and death. No correlations between the number of P. carinii organisms and the clinical course or outcome of the PCP, the symptoms before the FB or the paraclinical examinations were found. In conclusion, the routinely obtained quantitative results of the microbiological examinations of material from the lungs were not correlated to the severity of the PCP.",
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Pneumocystis carinii pneumonia in AIDS patients : clinical course in relation to the parasite number found in routine specimens obtained by fiberoptic bronchoscopy. / Orholm, Marianne; Nielsen, T L; Holten-Andersen, W; Lester, Anne; Kolmos, H J.

I: Scandinavian Journal of Infectious Diseases, Bind 24, Nr. 3, 1992, s. 301-7.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Pneumocystis carinii pneumonia in AIDS patients

T2 - clinical course in relation to the parasite number found in routine specimens obtained by fiberoptic bronchoscopy

AU - Orholm, Marianne

AU - Nielsen, T L

AU - Holten-Andersen, W

AU - Lester, Anne

AU - Kolmos, H J

PY - 1992

Y1 - 1992

N2 - The aim of this study was to evaluate whether the amount of Pneumocystis carinii organisms found at fiberoptic bronchoscopy (FB) performed on HIV-positive patients correlated to the character of the P. carinii pneumonia (PCP). A consecutive series of 105 patients presented with 131 episodes of pulmonary symptoms requiring FB, and in 75 of these episodes a diagnosis of PCP was made. Specimens were stained with Giemsa and methenamine silver nitrate and the number of parasites found was given as: numerous, many, few or none. The following signs and symptoms were registered: cough, dyspnoea, fever, loss of weight, chest radiograph, haemoglobin, WBC, CD4 cell count, PO2 and HIV p24 antigen. The PCP was characterized by the clinical course: mild, moderate, severe, and by the outcome: pulmonary healthy, pulmonary insufficiency and death. No correlations between the number of P. carinii organisms and the clinical course or outcome of the PCP, the symptoms before the FB or the paraclinical examinations were found. In conclusion, the routinely obtained quantitative results of the microbiological examinations of material from the lungs were not correlated to the severity of the PCP.

AB - The aim of this study was to evaluate whether the amount of Pneumocystis carinii organisms found at fiberoptic bronchoscopy (FB) performed on HIV-positive patients correlated to the character of the P. carinii pneumonia (PCP). A consecutive series of 105 patients presented with 131 episodes of pulmonary symptoms requiring FB, and in 75 of these episodes a diagnosis of PCP was made. Specimens were stained with Giemsa and methenamine silver nitrate and the number of parasites found was given as: numerous, many, few or none. The following signs and symptoms were registered: cough, dyspnoea, fever, loss of weight, chest radiograph, haemoglobin, WBC, CD4 cell count, PO2 and HIV p24 antigen. The PCP was characterized by the clinical course: mild, moderate, severe, and by the outcome: pulmonary healthy, pulmonary insufficiency and death. No correlations between the number of P. carinii organisms and the clinical course or outcome of the PCP, the symptoms before the FB or the paraclinical examinations were found. In conclusion, the routinely obtained quantitative results of the microbiological examinations of material from the lungs were not correlated to the severity of the PCP.

KW - Acquired Immunodeficiency Syndrome

KW - Adult

KW - Aged

KW - Bronchoscopy

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Pneumocystis

KW - Pneumonia, Pneumocystis

KW - Severity of Illness Index

KW - Journal Article

M3 - Journal article

VL - 24

SP - 301

EP - 307

JO - Infectious Diseases

JF - Infectious Diseases

SN - 2374-4235

IS - 3

ER -