Platform trials

Anders Perner, Maj Brit N. Kjær, Hans Christian Thorsen-Meyer, Benjamin S. Kaas-Hansen, Marie W. Munch, Marie O. Collet, Camilla Rl Bruun, Aksel Kg Jensen, Theis Lange, Trine Albertsen, Claus Duedal Pedersen, Lone M. Poulsen, Ole Mathiesen, Anne C. Brøchner, Thomas Strøm, Lars W. Andersen, Steffen Christensen, Bodil S. Rasmussen, Olav L. Schjørring, Mathias MaagaardMorten Hylander Møller, Anders Granholm

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstract

Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.

OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind185
Udgave nummer41
ISSN0041-5782
StatusUdgivet - 9. okt. 2023

Bibliografisk note

Publisher Copyright:
Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

Emneord

  • COVID-19/epidemiology
  • Humans
  • Pandemics

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