Plasma HER2 amplification in cell-free DNA during neoadjuvant chemotherapy in breast cancer

Troels Bechmann, Rikke Fredslund Andersen, Niels Pallisgaard, Jonna Skov Madsen, Else Maae, E. H. Jakobsen, Anne Marie Bak Jylling, Karina Dahl Steffensen, Anders Jakobsen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstract

Measurement of human epidermal growth factor receptor 2 (HER2) gene amplification in cell-free DNA (cfDNA) is an evolving technique in breast cancer, enabling liquid biopsies and treatment monitoring. The present study investigated the dynamics of plasma HER2 gene copy number and amplification in cfDNA during neoadjuvant chemotherapy.
OriginalsprogEngelsk
TidsskriftJournal of Cancer Research and Clinical Oncology
Vol/bind139
Udgave nummer6
Sider (fra-til)995-1003
Antal sider9
ISSN0171-5216
DOI
StatusUdgivet - jun. 2013

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