Persisterende pulmonal hypertension hos nyfødte

C M Pedersen, T G Hansen, Steen Winther Henneberg, Tom Giedsing Hansen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

On the basis of a review of the literature, a survey is presented concerning persistent pulmonary hypertension of the newborn. In this article the authors focus on the pathophysiology, diagnostic criteria and treatment, including mechanical ventilation, pharmacological vasodilation and extracorporal membrane oxygenation. Particular emphasis is placed on the treatment of the condition with inhaled nitric oxide. Nitric oxide is a selective pulmonary vasodilator and able to improve ventilation/ perfusion mismatching in cases where there is an affection of the pulmonary parenchyma. Data from randomized trials with close long-term follow-up is necessary before routine nitrogen oxide treatment can be recommended.
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind159
Udgave nummer28
Sider (fra-til)4377-82
Antal sider6
ISSN0041-5782
StatusUdgivet - 1997

Fingeraftryk

Persistent Fetal Circulation Syndrome
Nitric Oxide
Newborn Infant
Lung
Vasodilation
Ventilation
Perfusion
Membranes

Emneord

  • Humans
  • Infant, Newborn
  • Persistent Fetal Circulation Syndrome

Citer dette

Pedersen, C M ; Hansen, T G ; Henneberg, Steen Winther ; Hansen, Tom Giedsing. / Persisterende pulmonal hypertension hos nyfødte. I: Ugeskrift for Laeger. 1997 ; Bind 159, Nr. 28. s. 4377-82.
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Pedersen, CM, Hansen, TG, Henneberg, SW & Hansen, TG 1997, 'Persisterende pulmonal hypertension hos nyfødte', Ugeskrift for Laeger, bind 159, nr. 28, s. 4377-82.

Persisterende pulmonal hypertension hos nyfødte. / Pedersen, C M; Hansen, T G; Henneberg, Steen Winther; Hansen, Tom Giedsing.

I: Ugeskrift for Laeger, Bind 159, Nr. 28, 1997, s. 4377-82.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Persisterende pulmonal hypertension hos nyfødte

AU - Pedersen, C M

AU - Hansen, T G

AU - Henneberg, Steen Winther

AU - Hansen, Tom Giedsing

PY - 1997

Y1 - 1997

N2 - On the basis of a review of the literature, a survey is presented concerning persistent pulmonary hypertension of the newborn. In this article the authors focus on the pathophysiology, diagnostic criteria and treatment, including mechanical ventilation, pharmacological vasodilation and extracorporal membrane oxygenation. Particular emphasis is placed on the treatment of the condition with inhaled nitric oxide. Nitric oxide is a selective pulmonary vasodilator and able to improve ventilation/ perfusion mismatching in cases where there is an affection of the pulmonary parenchyma. Data from randomized trials with close long-term follow-up is necessary before routine nitrogen oxide treatment can be recommended.

AB - On the basis of a review of the literature, a survey is presented concerning persistent pulmonary hypertension of the newborn. In this article the authors focus on the pathophysiology, diagnostic criteria and treatment, including mechanical ventilation, pharmacological vasodilation and extracorporal membrane oxygenation. Particular emphasis is placed on the treatment of the condition with inhaled nitric oxide. Nitric oxide is a selective pulmonary vasodilator and able to improve ventilation/ perfusion mismatching in cases where there is an affection of the pulmonary parenchyma. Data from randomized trials with close long-term follow-up is necessary before routine nitrogen oxide treatment can be recommended.

KW - Humans

KW - Infant, Newborn

KW - Persistent Fetal Circulation Syndrome

M3 - Tidsskriftartikel

VL - 159

SP - 4377

EP - 4382

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

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