Persistente fluorforbindelser reducerer immunfunktionen

Carsten Heilmann, Lise Jensen, Pal Weihe, Flemming Nielsen, Lisbeth E Knudsen, Esben Budtz-Jørgensen, Kåre Mølbak, Philippe Grandjean

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

Perfluorinated compounds are highly stable and useful industrial chemicals. Both perfluorooctane sulfonic acid and perfluorooctanoic acid cause immunotoxic effects in animal models at serum concentrations similar to human levels. In children who have undergone routine vaccinations, serum concentrations of these substances are inversely associated with concentrations of antibodies against diphtheria and tetanus. Prevention of such effects will require a decrease of exposure limits by at least 100-fold. Immunotoxicity is not included in routine testing of industrial chemicals but urgently needs attention.

OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind176
Udgave nummer9A
Sider (fra-til)2-5
ISSN0041-5782
StatusUdgivet - 24. feb. 2014

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Citationsformater

Heilmann, C., Jensen, L., Weihe, P., Nielsen, F., Knudsen, L. E., Budtz-Jørgensen, E., Mølbak, K., & Grandjean, P. (2014). Persistente fluorforbindelser reducerer immunfunktionen. Ugeskrift for Laeger, 176(9A), 2-5.