Abstrakt
Meta-analyses of cohort studies and a recent randomized, placebo-controlled study have shown that perioperative bridging of warfarin therapy with therapeutic doses of heparin results in a multi-fold increase in major bleeding but no reduction in the incidence of thromboembolism. It is time to reconsider heparin bridging: When is heparin bridging superfluous? When is prophylactic dosage indicated? And when is it safe to use therapeutic dosing?
Bidragets oversatte titel | Perioperative heparin bridging is rarely indicated |
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Originalsprog | Dansk |
Artikelnummer | V12150952 |
Tidsskrift | Ugeskrift for Læger |
Vol/bind | 178 |
Udgave nummer | 12 |
ISSN | 0041-5782 |
Status | Udgivet - 2016 |
Udgivet eksternt | Ja |