Percutaneous ultrasound-guided cryoablation of renal grafts tumours

Janni Lynggård Bo Madsen, Tommy Kjaergaard Nielsen, Jan Solvig, Ole Graumann

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Abstrakt

Background
Tumours in renal grafts are rare with an estimated prevalence of 0.18% (1). An increased incidence of graft tumours may be observed in the future due to increased donor age and prolonged graft survival. Furthermore, the immunosuppressant state of the graft recipients may cause the tumour to behave more aggressively (2). In these complex cases, a minimal invasive nephron sparing treatment option, that can keep patients from the need of dialysis, is strongly warranted. Percutaneous cryoablation (Cryo) is a minimally invasive and worldwide well-established treatment option for both benign and malignant kidney tumours (3). Cryo often entails a shorter period of hospitalisation compared to more invasive procedures (3).

The aim of this case report is to describe Cryo as a treatment option for tumours in renal grafts.

Patient cases
Case 1: A 42-year-old female with a well-functioning ten years old graft with a 3x4x4 cm clear cell carcinoma. Case 2: A 70-year-old male with a well-functioning 15 years old graft with a 2x2x2 cm type-1 papillary adenocarcinoma. Both patients received percutaneous ultrasound-guided cryo in general anaesthesia with the patient placed in a lateral recumbent position. The tumours were treated using five cryoprobes and one temperature sensor for monitoring. The patients experienced no complications and were discharged the following day.

Case 1: The four-year follow-up MRI examinations revealed no signs of recurrent or metastatic disease. The patient refused further follow-up examinations, but remains free of dialysis.
Case 2: The one-year follow-up MRI examinations revealed no signs of recurrent or metastatic disease. The patient will be offered annual MRI for a total of five years follow-up.

Conclusion
We presented two cases of renal cell carcinoma in renal grafts which were successfully treated using percutaneous ultrasound-guided cryoablation: A minimal invasive technique in which only the tumour is destroyed and the graft function is preserved.
OriginalsprogEngelsk
Publikationsdato10. okt. 2020
StatusUdgivet - 10. okt. 2020
BegivenhedThe 26th Meeting of the European Association of Urology Research 2019 - Porto, Portugal
Varighed: 10. okt. 201912. okt. 2019
https://esur.uroweb.org/

Konference

KonferenceThe 26th Meeting of the European Association of Urology Research 2019
LandPortugal
ByPorto
Periode10/10/201912/10/2019
Internetadresse

Citationsformater

Lynggård Bo Madsen, J., Nielsen, T. K., Solvig, J., & Graumann, O. (2020). Percutaneous ultrasound-guided cryoablation of renal grafts tumours. Poster session præsenteret på The 26th Meeting of the European Association of Urology Research 2019, Porto, Portugal.