PDX1- and NGN3-mediated in vitro reprogramming of human bone marrow-derived mesenchymal stromal cells into pancreatic endocrine lineages

Catarina Limbert, Günter Päth, Regina Ebert, Veit Rothhammer, Moustapha Kassem, Franz Jakob, Jochen Seufert

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

Reprogramming of multipotent adult bone marrow (BM)-derived mesenchymal stromal/stem cells (MSC) (BM-MSC) represents one of several strategies for cell-based therapy of diabetes. However, reprogramming primary BM-MSC into pancreatic endocrine lineages has not yet been consistently demonstrated.
OriginalsprogEngelsk
TidsskriftCytotherapy
Vol/bind13
Udgave nummer7
Sider (fra-til)802-13
Antal sider12
ISSN1465-3249
DOI
StatusUdgivet - 2011

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