Objective: While the ability to recall medical information is crucial, it is known to be a considerable challenge for many patients. Consequently, we aimed to investigate whether replay could enhance information recall and to explore the extent of information recall in a group of Danish outpatients. Methods: This study utilized a mixed-methods approach and evaluated patients’ recall by comparing seven key themes between the interviews and the recordings. A total of 33 patients were included from three outpatient clinics. Results: Overall, 61% of the information was recalled. However, the study could not confirm an effect of replay on patients’ information recall. Information recall was associated with age and information load. Accordingly, patients younger than 70 years had a 2.46 higher probability of recall (95%CI: 1.1–5.5, p = 0.027), whereas an increase in information load negatively influenced recall. Conclusion: The study power is insufficient to provide a definite answer to the hypothesis regarding a positive association between replay and recall. Patients’ information recall depended on the information theme, their age, and amount of information provided in the consultation. Practice implications: The critical consequences of information overload necessitate an increased awareness of how to prioritise information, particularly when communicating with older patients.