Optical microassembly platform for constructing reconfigurable microenvironment for biomedical studies

Peter John Rodrigo, Lóránd Kelemen, Darwin Palima, Carlo Amadeo Alonzo, Pál Ormos, Jesper Glückstad

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Abstrakt

Cellular development is highly influenced by the surrounding microenvironment. We propose user-reconfigurable microenvironments and bio-compatible scaffolds as an approach for understanding cellular development processes. We demonstrate a model platform for constructing versatile microenvironments by fabricating morphologically complex microstructures by two-photon polymerization (2PP) and then assembling these archetypal building blocks into various configurations using multiple, real-time configurable counterpropagating-beam (CB) traps. The demonstrated capacity for handling feature-rich microcomponents may be further developed into a eneralized microassembly platform.
OriginalsprogEngelsk
TidsskriftOptics Express
Vol/bind17
Udgave nummer8
Sider (fra-til)6578-6583
ISSN1094-4087
DOI
StatusUdgivet - 2009
Udgivet eksterntJa

Bibliografisk note

OCIS codes: (170.0170) Medical optics and biotechnology; (170.4520) Optical confinement and manipulation; (230.40000) microstructure fabrication This paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/oe/abstract.cfm?uri=oe-17-8-6578. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.

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