Optical Imaging of Cells with Gold Nanoparticle Clusters as Light Scattering Contrast Agents: A Finite-Difference Time-Domain Approach to the Modeling of Flow Cytometry Configurations

Stoyan Tanev, Wenbo Sun, James Pond, Valery Tuchin*, Vladimir Zharov

*Kontaktforfatter for dette arbejde

Publikation: Kapitel i bog/rapport/konference-proceedingKapitel i bogForskning

Abstrakt

This chapter has two main objectives. First, to review a number of examples
illustrating the application of the FDTD approach to the modeling of some typical
light scattering configurations that could be associated with flow cytometry.
Second, to provide a thorough discussion of these new developments in advanced
cytometry research by pointing out potential new research directions. A brief
description of the FDTD method focusing on the features associated with its
application to modeling of light scattering and OPCM cell imaging experiments
is provided. The examples include light scattering from OPCM imaging of single
biological cells in conditions of controlled refractive index matching (RIM) and
labeling by diffused and clustered gold NPs. The chapter concludes with a
discussion and suggestions for future research.
OriginalsprogEngelsk
TitelAdvanced Optical Flow Cytometry : Methods and Disease Diagnoses
RedaktørerValery Tuchin
UdgivelsesstedWeinheim, Germany
ForlagWiley-VCH
Publikationsdato2011
Sider35-62
Kapitel3
ISBN (Trykt)978-3-527-40934-1
ISBN (Elektronisk)978-3-527-63429-3
DOI
StatusUdgivet - 2011

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