Number of hospital contacts with alcohol problems predicts later risk of alcoholic liver cirrhosis

Gro Askgaard, Janne S Tolstrup, Mette S Kjær, David A Leon

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

20 Downloads (Pure)

Resumé

AIMS: Alcoholic liver cirrhosis is usually preceded by years of heavy drinking. We investigated whether the risk of alcoholic liver cirrhosis increases as the number of hospital contacts with alcohol problems goes up.

METHODS: This was a supplementary analysis on a nationwide register-based cohort study. All patients in Denmark with an initial hospital contact with alcohol problems (alcohol intoxication, harmful alcohol use or alcohol dependence) 1998-2002, free of liver disease, were followed for diagnosis of alcoholic liver cirrhosis. The number of subsequent hospital contacts with alcohol problems was estimated as a time-dependent variable for each patient.

RESULTS: In all, 36,044 hospital patients with an initial hospital contact with alcohol problems were included. These patients had 301,525 subsequent hospital contacts with alcohol problems. Risk of alcoholic liver cirrhosis increased ( p < 0.0001) with number of alcohol hospital contacts in both men and women for up to nine contacts.

CONCLUSIONS: The number of prior hospital contacts with alcohol problems might provide clinicians with a helpful metric in deciding whether to offer preventive interventions for alcoholic liver cirrhosis.

OriginalsprogEngelsk
TidsskriftScandinavian Journal of Public Health
Vol/bind47
Udgave nummer4
Sider (fra-til)417-419
ISSN1403-4948
DOI
StatusUdgivet - jun. 2019

Fingeraftryk

Alcoholic Liver Cirrhosis
Alcohols
Alcoholic Intoxication
Denmark
Alcoholism
Drinking
Liver Diseases
Cohort Studies

Emneord

    Citer dette

    @article{1d661485a6254309a5743aa59662f00d,
    title = "Number of hospital contacts with alcohol problems predicts later risk of alcoholic liver cirrhosis",
    abstract = "AIMS: Alcoholic liver cirrhosis is usually preceded by years of heavy drinking. We investigated whether the risk of alcoholic liver cirrhosis increases as the number of hospital contacts with alcohol problems goes up.METHODS: This was a supplementary analysis on a nationwide register-based cohort study. All patients in Denmark with an initial hospital contact with alcohol problems (alcohol intoxication, harmful alcohol use or alcohol dependence) 1998-2002, free of liver disease, were followed for diagnosis of alcoholic liver cirrhosis. The number of subsequent hospital contacts with alcohol problems was estimated as a time-dependent variable for each patient.RESULTS: In all, 36,044 hospital patients with an initial hospital contact with alcohol problems were included. These patients had 301,525 subsequent hospital contacts with alcohol problems. Risk of alcoholic liver cirrhosis increased ( p < 0.0001) with number of alcohol hospital contacts in both men and women for up to nine contacts.CONCLUSIONS: The number of prior hospital contacts with alcohol problems might provide clinicians with a helpful metric in deciding whether to offer preventive interventions for alcoholic liver cirrhosis.",
    keywords = "alcoholic liver disease, cohort study, epidemiology, hospital contacts, prevention, Humans, Risk Factors, Alcoholic Intoxication/therapy, Male, Denmark, Female, Liver Cirrhosis, Alcoholic/diagnosis, Hospitals/statistics & numerical data, Alcoholism/therapy",
    author = "Gro Askgaard and Tolstrup, {Janne S} and Kj{\ae}r, {Mette S} and Leon, {David A}",
    year = "2019",
    month = "6",
    doi = "10.1177/1403494818763436",
    language = "English",
    volume = "47",
    pages = "417--419",
    journal = "Scandinavian Journal of Public Health",
    issn = "1403-4948",
    publisher = "SAGE Publications",
    number = "4",

    }

    Number of hospital contacts with alcohol problems predicts later risk of alcoholic liver cirrhosis. / Askgaard, Gro; Tolstrup, Janne S; Kjær, Mette S; Leon, David A.

    I: Scandinavian Journal of Public Health, Bind 47, Nr. 4, 06.2019, s. 417-419.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

    TY - JOUR

    T1 - Number of hospital contacts with alcohol problems predicts later risk of alcoholic liver cirrhosis

    AU - Askgaard, Gro

    AU - Tolstrup, Janne S

    AU - Kjær, Mette S

    AU - Leon, David A

    PY - 2019/6

    Y1 - 2019/6

    N2 - AIMS: Alcoholic liver cirrhosis is usually preceded by years of heavy drinking. We investigated whether the risk of alcoholic liver cirrhosis increases as the number of hospital contacts with alcohol problems goes up.METHODS: This was a supplementary analysis on a nationwide register-based cohort study. All patients in Denmark with an initial hospital contact with alcohol problems (alcohol intoxication, harmful alcohol use or alcohol dependence) 1998-2002, free of liver disease, were followed for diagnosis of alcoholic liver cirrhosis. The number of subsequent hospital contacts with alcohol problems was estimated as a time-dependent variable for each patient.RESULTS: In all, 36,044 hospital patients with an initial hospital contact with alcohol problems were included. These patients had 301,525 subsequent hospital contacts with alcohol problems. Risk of alcoholic liver cirrhosis increased ( p < 0.0001) with number of alcohol hospital contacts in both men and women for up to nine contacts.CONCLUSIONS: The number of prior hospital contacts with alcohol problems might provide clinicians with a helpful metric in deciding whether to offer preventive interventions for alcoholic liver cirrhosis.

    AB - AIMS: Alcoholic liver cirrhosis is usually preceded by years of heavy drinking. We investigated whether the risk of alcoholic liver cirrhosis increases as the number of hospital contacts with alcohol problems goes up.METHODS: This was a supplementary analysis on a nationwide register-based cohort study. All patients in Denmark with an initial hospital contact with alcohol problems (alcohol intoxication, harmful alcohol use or alcohol dependence) 1998-2002, free of liver disease, were followed for diagnosis of alcoholic liver cirrhosis. The number of subsequent hospital contacts with alcohol problems was estimated as a time-dependent variable for each patient.RESULTS: In all, 36,044 hospital patients with an initial hospital contact with alcohol problems were included. These patients had 301,525 subsequent hospital contacts with alcohol problems. Risk of alcoholic liver cirrhosis increased ( p < 0.0001) with number of alcohol hospital contacts in both men and women for up to nine contacts.CONCLUSIONS: The number of prior hospital contacts with alcohol problems might provide clinicians with a helpful metric in deciding whether to offer preventive interventions for alcoholic liver cirrhosis.

    KW - alcoholic liver disease

    KW - cohort study

    KW - epidemiology

    KW - hospital contacts

    KW - prevention

    KW - Humans

    KW - Risk Factors

    KW - Alcoholic Intoxication/therapy

    KW - Male

    KW - Denmark

    KW - Female

    KW - Liver Cirrhosis, Alcoholic/diagnosis

    KW - Hospitals/statistics & numerical data

    KW - Alcoholism/therapy

    U2 - 10.1177/1403494818763436

    DO - 10.1177/1403494818763436

    M3 - Journal article

    VL - 47

    SP - 417

    EP - 419

    JO - Scandinavian Journal of Public Health

    JF - Scandinavian Journal of Public Health

    SN - 1403-4948

    IS - 4

    ER -