NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype

Mahmoud H. Elbatreek^*, Sepideh Sadegh, Elisa Anastasi, Emre Guney, Cristian Nogales, Tim Kacprowski, Ahmed A. Hassan, Andreas Teubner, Po Hsun Huang, Chien Yi Hsu, Paul M.H. Schiffers, Ger M. Janssen, Pamela W.M. Kleikers, Anil Wipat, Jan Baumbach, Jo G.R. De Mey, Harald H.H.W. Schmidt^*