No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus

Maja Døvling Kaspersen; Mona Berger Håkonsen Bungum; J Fedder; Jens Peter Bonde; P B Larsen; H J Ingerslev; Per Höllsberg

doi:10.1111/j.2047-2927.2013.00067.x

No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus

Maja Døvling Kaspersen^*
, Mona Berger Håkonsen Bungum
, J Fedder
, Jens Peter Bonde
, P B Larsen
, H J Ingerslev
, Per Höllsberg

^*Kontaktforfatter

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.

Originalsprog	Engelsk
Tidsskrift	Andrology
Vol/bind	1
Udgave nummer	3
Sider (fra-til)	361-364
ISSN	0196-3635
DOI	https://doi.org/10.1111/j.2047-2927.2013.00067.x
Status	Udgivet - maj 2013
Udgivet eksternt	Ja

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10.1111/j.2047-2927.2013.00067.x

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Tjek adgangen til materialet i Syddansk Universitetsbiblioteks søgemaskine

Citationsformater

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title = "No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus",

abstract = "It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57\% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.",

author = "Kaspersen, \{Maja D{\o}vling\} and Bungum, \{Mona Berger H{\aa}konsen\} and J Fedder and Bonde, \{Jens Peter\} and Larsen, \{P B\} and \{J Ingerslev\}, H and Per H{\"o}llsberg",

note = "{\textcopyright} 2013 American Society of Andrology and European Academy of Andrology.",

year = "2013",

month = may,

doi = "10.1111/j.2047-2927.2013.00067.x",

language = "English",

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T1 - No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus

AU - Kaspersen, Maja Døvling

AU - Bungum, Mona Berger Håkonsen

AU - Fedder, J

AU - Bonde, Jens Peter

AU - Larsen, P B

AU - J Ingerslev, H

AU - Höllsberg, Per

PY - 2013/5

Y1 - 2013/5

N2 - It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.

AB - It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.

U2 - 10.1111/j.2047-2927.2013.00067.x

DO - 10.1111/j.2047-2927.2013.00067.x

M3 - Journal article

C2 - 23444031

SN - 0196-3635

VL - 1

SP - 361

EP - 364

JO - Andrology

JF - Andrology

IS - 3

ER -

No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus

Abstract

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