Resumé
BACKGROUND: We wanted to characterize the use of Helicobacter pylori eradication therapy in Denmark (5,227,862 inhabitants).
METHODS: All H. pylori eradication treatments from a nationwide database including all redeemed drug prescriptions in the period January 1994 to June 1996 were identified. So were all outpatients receiving a drug prescription for H. pylori eradication.
RESULTS: We recorded 34,582 prescriptions for H. pylori eradication therapy given to 28,784 patients. The incidence of new consumers was 220 per 10(5) inhabitants per year, with a maximum at 70-79 years of age. Eighty-six per cent of the patients had only one treatment course. In 16% of the eradication therapies, nonsteroid anti-inflammatory drugs had been prescribed within the previous 3 months, and 45% had an anti-ulcer drug prescribed 1-12 months after the H. pylori eradication therapy. Consumption of antibiotics used for H. pylori eradication accounted for 1.4% of the total consumption of antibiotics.
CONCLUSIONS: The incidence of H. pylori eradication therapy was fairly stable but with changes in the pattern of drug regimens used. Anti-ulcer drugs were often given after H. pylori eradication therapy, suggesting an inappropriate use of treatment.
| Originalsprog | Engelsk |
|---|---|
| Bogserie | Scandinavian Journal of Gastroenterology. Supplement |
| Vol/bind | 33 |
| Udgave nummer | 9 |
| Sider (fra-til) | 928-32 |
| Antal sider | 5 |
| ISSN | 0036-5521 |
| Status | Udgivet - sep. 1998 |
Fingeraftryk
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National surveillance of Helicobacter pylori eradication therapy in Denmark. Results from registration of 34,582 prescriptions. / Juul, K.V.; Thomsen, V O; Nissen, A.; Hallas, J; Kolmos, H J; Funch-Jensen, P.; Lauritsen, K.
I: Scandinavian Journal of Gastroenterology. Supplement, Bind 33, Nr. 9, 09.1998, s. 928-32.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
TY - JOUR
T1 - National surveillance of Helicobacter pylori eradication therapy in Denmark. Results from registration of 34,582 prescriptions
AU - Juul, K.V.
AU - Thomsen, V O
AU - Nissen, A.
AU - Hallas, J
AU - Kolmos, H J
AU - Funch-Jensen, P.
AU - Lauritsen, K
PY - 1998/9
Y1 - 1998/9
N2 - BACKGROUND: We wanted to characterize the use of Helicobacter pylori eradication therapy in Denmark (5,227,862 inhabitants).METHODS: All H. pylori eradication treatments from a nationwide database including all redeemed drug prescriptions in the period January 1994 to June 1996 were identified. So were all outpatients receiving a drug prescription for H. pylori eradication.RESULTS: We recorded 34,582 prescriptions for H. pylori eradication therapy given to 28,784 patients. The incidence of new consumers was 220 per 10(5) inhabitants per year, with a maximum at 70-79 years of age. Eighty-six per cent of the patients had only one treatment course. In 16% of the eradication therapies, nonsteroid anti-inflammatory drugs had been prescribed within the previous 3 months, and 45% had an anti-ulcer drug prescribed 1-12 months after the H. pylori eradication therapy. Consumption of antibiotics used for H. pylori eradication accounted for 1.4% of the total consumption of antibiotics.CONCLUSIONS: The incidence of H. pylori eradication therapy was fairly stable but with changes in the pattern of drug regimens used. Anti-ulcer drugs were often given after H. pylori eradication therapy, suggesting an inappropriate use of treatment.
AB - BACKGROUND: We wanted to characterize the use of Helicobacter pylori eradication therapy in Denmark (5,227,862 inhabitants).METHODS: All H. pylori eradication treatments from a nationwide database including all redeemed drug prescriptions in the period January 1994 to June 1996 were identified. So were all outpatients receiving a drug prescription for H. pylori eradication.RESULTS: We recorded 34,582 prescriptions for H. pylori eradication therapy given to 28,784 patients. The incidence of new consumers was 220 per 10(5) inhabitants per year, with a maximum at 70-79 years of age. Eighty-six per cent of the patients had only one treatment course. In 16% of the eradication therapies, nonsteroid anti-inflammatory drugs had been prescribed within the previous 3 months, and 45% had an anti-ulcer drug prescribed 1-12 months after the H. pylori eradication therapy. Consumption of antibiotics used for H. pylori eradication accounted for 1.4% of the total consumption of antibiotics.CONCLUSIONS: The incidence of H. pylori eradication therapy was fairly stable but with changes in the pattern of drug regimens used. Anti-ulcer drugs were often given after H. pylori eradication therapy, suggesting an inappropriate use of treatment.
KW - Adolescent
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Amoxicillin
KW - Antacids
KW - Anti-Bacterial Agents
KW - Bismuth
KW - Child
KW - Denmark
KW - Drug Prescriptions
KW - Drug Therapy, Combination
KW - Female
KW - Health Care Surveys
KW - Helicobacter Infections
KW - Helicobacter pylori
KW - Histamine H2 Antagonists
KW - Humans
KW - Imidazoles
KW - Macrolides
KW - Male
KW - Middle Aged
KW - Penicillins
KW - Proton Pump Inhibitors
KW - Tetracyclines
KW - Journal Article
M3 - Journal article
C2 - 9759947
VL - 33
SP - 928
EP - 932
JO - Scandinavian Journal of Gastroenterology. Supplement
JF - Scandinavian Journal of Gastroenterology. Supplement
SN - 0085-5928
IS - 9
ER -