Purpose: The main purpose was to investigate whether MRI could be used in
the local staging of colonic cancer.
Material and Methods: The study is a prospective blinded observational
study. Patients had standard CT scans. For the MRI scan, a 3 Tesla MRI unit
was used. Experienced radiologists reported the scans blinded to the other
modality and pathological description. Surgery was performed within a median
of 7 days after the MDT. The resected specimens were classifed according to
the pTNM system. The endpoint of the study was the histopathological surgical specimen.
Results: From October 2019 to December 2020, 134 patients were included in
the study. CT was able to identify 118 of the 134 tumors, whereas MRI identifed all tumors. For discriminating T3ab and T3cd cancers, CT had a sensitivity and specifcity of 33.3% and 77%, whereas MRI had higher values with
55.6% and 100% (p<0.05). The CT had a sensitivity and specifcity in lymph
node involvement of 59.0% and 56.3%. The same values for MRI were 57.4%
and 54.2%, respectively. For the evaluation of extravascular involvement, CT
had a sensitivity of 33.3% and specifcity of 84.4%, whereas MRI had higher
values with a sensitivity of 54.1% and specifcity of 77.1%. The mean tumor
ADC value tended to be lower in patients with distant metastases compared
to those without. Tumors containing mucin had statistically signifcantly less
diffusion restriction.
Conclusion: MRI had higher sensitivity compared to CT in detecting advanced
T3 tumors. Diffusion-weighted MRI was supportive in the diagnosis of mucin
in colonic tumors.
TidsskriftInsights into Imaging
Udgave nummerSuppl 2
Sider (fra-til)9
Antal sider1
StatusUdgivet - 1. mar. 2022
BegivenhedEuropean Society of Gastrointestinal and
Abdominal Radiology 2022
- Lisbon, Lisbon, Portugal
Varighed: 31. maj 20223. jun. 2022
Konferencens nummer: 33


KonferenceEuropean Society of Gastrointestinal and
Abdominal Radiology 2022

Bibliografisk note

Insights into Imaging volume 13, Article number: 92 (2022)


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