Movement detection impaired in patients with knee osteoarthritis compared to healthy controls

A cross-sectional case-control study

H Lund, Birgit Juul-Kristensen, Klaus Hansen, Robin Christensen, Hanne Christensen, Bente Danneskiold-Samsoe, H Bliddal

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

The purpose of this study was to clarify whether osteoarthritis (OA) patients have a localized or a generalized reduction in proprioception. Twenty one women with knee OA (mean age [SD]: 57.1 [12.0] years) and 29 healthy women (mean age [SD]: 55.3 [10.1] years) had their joint position sense (JPS) and threshold to detection of a passive movement (TDPM) measured in both knees and elbows. JPS was measured as the participant's ability to actively reproduce the position of the elbow and knee joints. TDPM was measured as the participant's ability to recognize a passive motion of the elbow and knee joints. The absolute error (AE) for JPS (i.e., absolute difference in degrees between target and estimated position) and for TDPM (i.e., the difference in degrees at movement start and response when recognizing the movement) was calculated. For TDPM a higher AE (mean [SE]) was found in the involved knees in patients than in the matched knees of healthy participants (AE: 2.41(o) [0.20(o)] versus 1.47(o) [0.14], p=0.001). The same held true for the non-involved knees between OA and healthy subjects (AE: 2.20(o) [0.20(o)] versus 1.57(o) [0.14(o)], p=0.016). Furthermore TDPM was higher in OA patients' right elbows compared to healthy participants' right elbows (AE: 2.15(o) [0.20(o)] versus 1.45(o) [0.15(o)], p=0.011). No significant difference between healthy women and OA patients regarding the left elbow for TDPM, or JPS was observed. The present age-controlled, cross-sectional study suggests that there is an increase in threshold to detection of a passive motion in knees and elbows for patients with knee OA. This indicates that OA may be associated with a generalized defect in proprioception with possible implications for the pathogenesis of the joint degeneration.
OriginalsprogEngelsk
TidsskriftJournal of Musculoskeletal and Neuronal Interactions - JMNI
Vol/bind8
Udgave nummer4
Sider (fra-til)391-400
Antal sider9
ISSN1108-7161
StatusUdgivet - 2009

Fingeraftryk

Proprioception
Knee Osteoarthritis
Case-Control Studies
Elbow
Joints
Knee
Elbow Joint
Knee Joint
Patient Rights
Cross-Sectional Studies

Citer dette

Lund, H ; Juul-Kristensen, Birgit ; Hansen, Klaus ; Christensen, Robin ; Christensen, Hanne ; Danneskiold-Samsoe, Bente ; Bliddal, H. / Movement detection impaired in patients with knee osteoarthritis compared to healthy controls : A cross-sectional case-control study. I: Journal of Musculoskeletal and Neuronal Interactions - JMNI. 2009 ; Bind 8, Nr. 4. s. 391-400.
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title = "Movement detection impaired in patients with knee osteoarthritis compared to healthy controls: A cross-sectional case-control study",
abstract = "The purpose of this study was to clarify whether osteoarthritis (OA) patients have a localized or a generalized reduction in proprioception. Twenty one women with knee OA (mean age [SD]: 57.1 [12.0] years) and 29 healthy women (mean age [SD]: 55.3 [10.1] years) had their joint position sense (JPS) and threshold to detection of a passive movement (TDPM) measured in both knees and elbows. JPS was measured as the participant's ability to actively reproduce the position of the elbow and knee joints. TDPM was measured as the participant's ability to recognize a passive motion of the elbow and knee joints. The absolute error (AE) for JPS (i.e., absolute difference in degrees between target and estimated position) and for TDPM (i.e., the difference in degrees at movement start and response when recognizing the movement) was calculated. For TDPM a higher AE (mean [SE]) was found in the involved knees in patients than in the matched knees of healthy participants (AE: 2.41(o) [0.20(o)] versus 1.47(o) [0.14], p=0.001). The same held true for the non-involved knees between OA and healthy subjects (AE: 2.20(o) [0.20(o)] versus 1.57(o) [0.14(o)], p=0.016). Furthermore TDPM was higher in OA patients' right elbows compared to healthy participants' right elbows (AE: 2.15(o) [0.20(o)] versus 1.45(o) [0.15(o)], p=0.011). No significant difference between healthy women and OA patients regarding the left elbow for TDPM, or JPS was observed. The present age-controlled, cross-sectional study suggests that there is an increase in threshold to detection of a passive motion in knees and elbows for patients with knee OA. This indicates that OA may be associated with a generalized defect in proprioception with possible implications for the pathogenesis of the joint degeneration.",
author = "H Lund and Birgit Juul-Kristensen and Klaus Hansen and Robin Christensen and Hanne Christensen and Bente Danneskiold-Samsoe and H Bliddal",
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Movement detection impaired in patients with knee osteoarthritis compared to healthy controls : A cross-sectional case-control study. / Lund, H; Juul-Kristensen, Birgit; Hansen, Klaus; Christensen, Robin; Christensen, Hanne; Danneskiold-Samsoe, Bente; Bliddal, H.

I: Journal of Musculoskeletal and Neuronal Interactions - JMNI, Bind 8, Nr. 4, 2009, s. 391-400.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Movement detection impaired in patients with knee osteoarthritis compared to healthy controls

T2 - A cross-sectional case-control study

AU - Lund, H

AU - Juul-Kristensen, Birgit

AU - Hansen, Klaus

AU - Christensen, Robin

AU - Christensen, Hanne

AU - Danneskiold-Samsoe, Bente

AU - Bliddal, H

PY - 2009

Y1 - 2009

N2 - The purpose of this study was to clarify whether osteoarthritis (OA) patients have a localized or a generalized reduction in proprioception. Twenty one women with knee OA (mean age [SD]: 57.1 [12.0] years) and 29 healthy women (mean age [SD]: 55.3 [10.1] years) had their joint position sense (JPS) and threshold to detection of a passive movement (TDPM) measured in both knees and elbows. JPS was measured as the participant's ability to actively reproduce the position of the elbow and knee joints. TDPM was measured as the participant's ability to recognize a passive motion of the elbow and knee joints. The absolute error (AE) for JPS (i.e., absolute difference in degrees between target and estimated position) and for TDPM (i.e., the difference in degrees at movement start and response when recognizing the movement) was calculated. For TDPM a higher AE (mean [SE]) was found in the involved knees in patients than in the matched knees of healthy participants (AE: 2.41(o) [0.20(o)] versus 1.47(o) [0.14], p=0.001). The same held true for the non-involved knees between OA and healthy subjects (AE: 2.20(o) [0.20(o)] versus 1.57(o) [0.14(o)], p=0.016). Furthermore TDPM was higher in OA patients' right elbows compared to healthy participants' right elbows (AE: 2.15(o) [0.20(o)] versus 1.45(o) [0.15(o)], p=0.011). No significant difference between healthy women and OA patients regarding the left elbow for TDPM, or JPS was observed. The present age-controlled, cross-sectional study suggests that there is an increase in threshold to detection of a passive motion in knees and elbows for patients with knee OA. This indicates that OA may be associated with a generalized defect in proprioception with possible implications for the pathogenesis of the joint degeneration.

AB - The purpose of this study was to clarify whether osteoarthritis (OA) patients have a localized or a generalized reduction in proprioception. Twenty one women with knee OA (mean age [SD]: 57.1 [12.0] years) and 29 healthy women (mean age [SD]: 55.3 [10.1] years) had their joint position sense (JPS) and threshold to detection of a passive movement (TDPM) measured in both knees and elbows. JPS was measured as the participant's ability to actively reproduce the position of the elbow and knee joints. TDPM was measured as the participant's ability to recognize a passive motion of the elbow and knee joints. The absolute error (AE) for JPS (i.e., absolute difference in degrees between target and estimated position) and for TDPM (i.e., the difference in degrees at movement start and response when recognizing the movement) was calculated. For TDPM a higher AE (mean [SE]) was found in the involved knees in patients than in the matched knees of healthy participants (AE: 2.41(o) [0.20(o)] versus 1.47(o) [0.14], p=0.001). The same held true for the non-involved knees between OA and healthy subjects (AE: 2.20(o) [0.20(o)] versus 1.57(o) [0.14(o)], p=0.016). Furthermore TDPM was higher in OA patients' right elbows compared to healthy participants' right elbows (AE: 2.15(o) [0.20(o)] versus 1.45(o) [0.15(o)], p=0.011). No significant difference between healthy women and OA patients regarding the left elbow for TDPM, or JPS was observed. The present age-controlled, cross-sectional study suggests that there is an increase in threshold to detection of a passive motion in knees and elbows for patients with knee OA. This indicates that OA may be associated with a generalized defect in proprioception with possible implications for the pathogenesis of the joint degeneration.

M3 - Journal article

VL - 8

SP - 391

EP - 400

JO - Journal of Musculoskeletal and Neuronal Interactions

JF - Journal of Musculoskeletal and Neuronal Interactions

SN - 1108-7161

IS - 4

ER -