Monozygotic twin differences in perceived age

    Publikation: Kapitel i bog/rapport/konference-proceedingKapitel i bogForskningpeer review

    Abstract

    One of the possibilities to assess differences between monozygotic (MZ) twins, theoretically identical, is the perceived age as an estimate of biological age between MZ pairs. When we consider a lifelong exposure to environmental influences and insults of any sort, the initial more pronounced similarity between MZ twins will increasingly diverge with age. Despite the high heritability in perceived age, there is still a big absolute intrapair variation in this parameter between MZ twin pairs. Still the intrapair correlation was high even after age 70. Using data derived from the Danish Twin Registry, the authors investigated the relative influence of genetic and environmental factors on aging phenotypes. This chapter focuses on perceived age of MZ twins older than 70 years as a biomarker of aging and discuss how perceived age is associated with health and survival.

    OriginalsprogEngelsk
    TitelDevelopmental and Fetal Origins of Differences in Monozygotic Twins : From Genetics to Environmental Factors
    RedaktørerAlexandra Matias, Isaac Blickstein
    ForlagAcademic Press
    Publikationsdato2020
    Sider306-318
    Kapitel20
    ISBN (Trykt)9780128200476
    ISBN (Elektronisk)9780128203071
    DOI
    StatusUdgivet - 2020

    Emneord

    • Monozygotic twins
    • Differences
    • perceived age
    • environment
    • aging

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