MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis

S S Veidal, D V Larsen, Xijuan Chen, S Sun, Qiuju Zheng, Anne-Christine Bay Jensen, Diana Julie Leeming, A Nawrocki, Martin Røssel Larsen, G Schett, M A Karsdal

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Abstrakt

Type V collagen has been demonstrated to control fibril formation. The aim of this study was to develop an ELISA capable of detecting a fragment of type V collagen generated by MMP-2/9 and to evaluate the assay as biomarker for ankylosing spondylitis (AS).
OriginalsprogEngelsk
TidsskriftClinical Biochemistry
Vol/bind45
Udgave nummer7-8
Sider (fra-til)541-6
Antal sider6
ISSN0009-9120
DOI
StatusUdgivet - 2012

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