Meta-analysis of determinants for pet ownership in 12 European birth cohorts on asthma and allergies: a GA2LEN initiative

E Eller, S Roll, C-M Chen, O Herbarth, H-E Wichmann, A von Berg, U Krämer, M Mommers, C Thijs, A Wijga, B Brunekreef, M P Fantini, F Bravi, F Forastiere, D Porta, J Sunyer, M Torrent, A Høst, S Halken, K C Lødrup CarlsenK-H Carlsen, M Wickman, I Kull, U Wahn, S N Willich, S Lau, T Keil, J Heinrich

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Udgivelsesdato: 2008-Nov
OriginalsprogEngelsk
TidsskriftAllergy. European Journal of Allergy and Clinical Immunology
Vol/bind63
Udgave nummer11
Sider (fra-til)1491-8
Antal sider7
ISSN0105-4538
DOI
StatusUdgivet - 1. nov. 2008

Fingeraftryk

Ownership
Meta-Analysis
Hypersensitivity
Cats
Dogs
Siblings
Cohort Studies
Parents
Social Adjustment
Crowding
Eczema
Education

Citer dette

Eller, E ; Roll, S ; Chen, C-M ; Herbarth, O ; Wichmann, H-E ; von Berg, A ; Krämer, U ; Mommers, M ; Thijs, C ; Wijga, A ; Brunekreef, B ; Fantini, M P ; Bravi, F ; Forastiere, F ; Porta, D ; Sunyer, J ; Torrent, M ; Høst, A ; Halken, S ; Lødrup Carlsen, K C ; Carlsen, K-H ; Wickman, M ; Kull, I ; Wahn, U ; Willich, S N ; Lau, S ; Keil, T ; Heinrich, J. / Meta-analysis of determinants for pet ownership in 12 European birth cohorts on asthma and allergies: a GA2LEN initiative. I: Allergy. European Journal of Allergy and Clinical Immunology. 2008 ; Bind 63, Nr. 11. s. 1491-8.
@article{eefd2e00059511dfaefb000ea68e967b,
title = "Meta-analysis of determinants for pet ownership in 12 European birth cohorts on asthma and allergies: a GA2LEN initiative",
abstract = "BACKGROUND: Studies on pet ownership as a risk or protective factor for asthma and allergy show inconsistent results. This may be on account of insufficient adjustment of confounding factors. AIM: The objective of this study was to describe determinants of cat and dog ownership in European families with and without allergies. METHODS: Within the EU-funded network of excellence GA(2)LEN, we performed meta-analyses with data from 12 ongoing European birth cohort studies on asthma and allergy. Each of the birth cohort studies enrolled between 485 and 4089 children. Pet ownership, allergic status (asthma, allergic rhinitis, eczema) of parents and siblings, parental education, access to ground floor, and number of people living at home were assessed by questionnaires. RESULTS: Among the 25 056 families from seven European countries cats (14.9{\%}) were more common than dogs (12.0{\%}). Allergic family history significantly reduced the odds to own a cat (adjusted combined random-effect OR 0.91; 95{\%} CI 0.85-0.99), or dog (0.90; 0.86-0.94). A higher parental educational level had even more pronounced effects on cat (0.84; 0.71-0.98), and dog ownership (0.61; 0.54-0.70). Elder siblings reduced the odds to own cats, but not dogs. Convenient ground access significantly increased the odds, whereas crowding at home was not associated with cat or dog ownership. CONCLUSIONS: The chances to own a cat or dog were significantly reduced in allergic families, in parents with a higher educational level, and in homes without convenient ground access. In addition to parental allergies, social and housing factors should be considered as potential confounders in studies on pet exposure and allergic diseases.",
keywords = "Air Pollution, Indoor, Allergens, Animals, Cats, Cohort Studies, Dogs, Family Characteristics, Humans, Hypersensitivity, Questionnaires",
author = "E Eller and S Roll and C-M Chen and O Herbarth and H-E Wichmann and {von Berg}, A and U Kr{\"a}mer and M Mommers and C Thijs and A Wijga and B Brunekreef and Fantini, {M P} and F Bravi and F Forastiere and D Porta and J Sunyer and M Torrent and A H{\o}st and S Halken and {L{\o}drup Carlsen}, {K C} and K-H Carlsen and M Wickman and I Kull and U Wahn and Willich, {S N} and S Lau and T Keil and J Heinrich",
year = "2008",
month = "11",
day = "1",
doi = "10.1111/j.1398-9995.2008.01790.x",
language = "English",
volume = "63",
pages = "1491--8",
journal = "Allergy: European Journal of Allergy and Clinical Immunology",
issn = "0105-4538",
publisher = "Wiley Online",
number = "11",

}

Eller, E, Roll, S, Chen, C-M, Herbarth, O, Wichmann, H-E, von Berg, A, Krämer, U, Mommers, M, Thijs, C, Wijga, A, Brunekreef, B, Fantini, MP, Bravi, F, Forastiere, F, Porta, D, Sunyer, J, Torrent, M, Høst, A, Halken, S, Lødrup Carlsen, KC, Carlsen, K-H, Wickman, M, Kull, I, Wahn, U, Willich, SN, Lau, S, Keil, T & Heinrich, J 2008, 'Meta-analysis of determinants for pet ownership in 12 European birth cohorts on asthma and allergies: a GA2LEN initiative', Allergy. European Journal of Allergy and Clinical Immunology, bind 63, nr. 11, s. 1491-8. https://doi.org/10.1111/j.1398-9995.2008.01790.x

Meta-analysis of determinants for pet ownership in 12 European birth cohorts on asthma and allergies: a GA2LEN initiative. / Eller, E; Roll, S; Chen, C-M; Herbarth, O; Wichmann, H-E; von Berg, A; Krämer, U; Mommers, M; Thijs, C; Wijga, A; Brunekreef, B; Fantini, M P; Bravi, F; Forastiere, F; Porta, D; Sunyer, J; Torrent, M; Høst, A; Halken, S; Lødrup Carlsen, K C; Carlsen, K-H; Wickman, M; Kull, I; Wahn, U; Willich, S N; Lau, S; Keil, T; Heinrich, J.

I: Allergy. European Journal of Allergy and Clinical Immunology, Bind 63, Nr. 11, 01.11.2008, s. 1491-8.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Meta-analysis of determinants for pet ownership in 12 European birth cohorts on asthma and allergies: a GA2LEN initiative

AU - Eller, E

AU - Roll, S

AU - Chen, C-M

AU - Herbarth, O

AU - Wichmann, H-E

AU - von Berg, A

AU - Krämer, U

AU - Mommers, M

AU - Thijs, C

AU - Wijga, A

AU - Brunekreef, B

AU - Fantini, M P

AU - Bravi, F

AU - Forastiere, F

AU - Porta, D

AU - Sunyer, J

AU - Torrent, M

AU - Høst, A

AU - Halken, S

AU - Lødrup Carlsen, K C

AU - Carlsen, K-H

AU - Wickman, M

AU - Kull, I

AU - Wahn, U

AU - Willich, S N

AU - Lau, S

AU - Keil, T

AU - Heinrich, J

PY - 2008/11/1

Y1 - 2008/11/1

N2 - BACKGROUND: Studies on pet ownership as a risk or protective factor for asthma and allergy show inconsistent results. This may be on account of insufficient adjustment of confounding factors. AIM: The objective of this study was to describe determinants of cat and dog ownership in European families with and without allergies. METHODS: Within the EU-funded network of excellence GA(2)LEN, we performed meta-analyses with data from 12 ongoing European birth cohort studies on asthma and allergy. Each of the birth cohort studies enrolled between 485 and 4089 children. Pet ownership, allergic status (asthma, allergic rhinitis, eczema) of parents and siblings, parental education, access to ground floor, and number of people living at home were assessed by questionnaires. RESULTS: Among the 25 056 families from seven European countries cats (14.9%) were more common than dogs (12.0%). Allergic family history significantly reduced the odds to own a cat (adjusted combined random-effect OR 0.91; 95% CI 0.85-0.99), or dog (0.90; 0.86-0.94). A higher parental educational level had even more pronounced effects on cat (0.84; 0.71-0.98), and dog ownership (0.61; 0.54-0.70). Elder siblings reduced the odds to own cats, but not dogs. Convenient ground access significantly increased the odds, whereas crowding at home was not associated with cat or dog ownership. CONCLUSIONS: The chances to own a cat or dog were significantly reduced in allergic families, in parents with a higher educational level, and in homes without convenient ground access. In addition to parental allergies, social and housing factors should be considered as potential confounders in studies on pet exposure and allergic diseases.

AB - BACKGROUND: Studies on pet ownership as a risk or protective factor for asthma and allergy show inconsistent results. This may be on account of insufficient adjustment of confounding factors. AIM: The objective of this study was to describe determinants of cat and dog ownership in European families with and without allergies. METHODS: Within the EU-funded network of excellence GA(2)LEN, we performed meta-analyses with data from 12 ongoing European birth cohort studies on asthma and allergy. Each of the birth cohort studies enrolled between 485 and 4089 children. Pet ownership, allergic status (asthma, allergic rhinitis, eczema) of parents and siblings, parental education, access to ground floor, and number of people living at home were assessed by questionnaires. RESULTS: Among the 25 056 families from seven European countries cats (14.9%) were more common than dogs (12.0%). Allergic family history significantly reduced the odds to own a cat (adjusted combined random-effect OR 0.91; 95% CI 0.85-0.99), or dog (0.90; 0.86-0.94). A higher parental educational level had even more pronounced effects on cat (0.84; 0.71-0.98), and dog ownership (0.61; 0.54-0.70). Elder siblings reduced the odds to own cats, but not dogs. Convenient ground access significantly increased the odds, whereas crowding at home was not associated with cat or dog ownership. CONCLUSIONS: The chances to own a cat or dog were significantly reduced in allergic families, in parents with a higher educational level, and in homes without convenient ground access. In addition to parental allergies, social and housing factors should be considered as potential confounders in studies on pet exposure and allergic diseases.

KW - Air Pollution, Indoor

KW - Allergens

KW - Animals

KW - Cats

KW - Cohort Studies

KW - Dogs

KW - Family Characteristics

KW - Humans

KW - Hypersensitivity

KW - Questionnaires

U2 - 10.1111/j.1398-9995.2008.01790.x

DO - 10.1111/j.1398-9995.2008.01790.x

M3 - Journal article

C2 - 18721248

VL - 63

SP - 1491

EP - 1498

JO - Allergy: European Journal of Allergy and Clinical Immunology

JF - Allergy: European Journal of Allergy and Clinical Immunology

SN - 0105-4538

IS - 11

ER -