Menstruationsforstyrrelser ved insulinkraevende diabetes mellitus--epidemiologi og årsager

R K Støving; J Hangaard; K K Pedersen; C Hagen

Menstruationsforstyrrelser ved insulinkraevende diabetes mellitus--epidemiologi og årsager

R K Støving, J Hangaard, K K Pedersen, C Hagen

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

About 20% of all women with insulin-dependent diabetes mellitus (IDDM) have menstrual irregularities. Eight percent have amenorrhea. Fluctuations in blood glucose and insulin concentration are probably contributing factors, but the irregular menstrual cycles are mainly caused by disorders in the central ovulatory mechanisms. Hypothalamic GnRH release is regulated by several neuropeptides. Dopamine and opiates exert an inhibitory effect, and there is evidence for an abnormally high dopaminergic hypothalamic activity among women with IDDM. There might also be disorders of the opioid, serotonergic and GABA'ergic systems, but the consequences of there possibilities remain uncertain.
Udgivelsesdato: 1994-Oct-17

Bidragets oversatte titel	Menstruation disorders in insulin-dependent diabetes mellitus--epidemiology and causes
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Læger
Vol/bind	156
Udgave nummer	42
Sider (fra-til)	6180-4
Antal sider	4
ISSN	0041-5782
Status	Udgivet - 1994

Citationsformater

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title = "Menstruationsforstyrrelser ved insulinkraevende diabetes mellitus--epidemiologi og {\aa}rsager",

abstract = "About 20% of all women with insulin-dependent diabetes mellitus (IDDM) have menstrual irregularities. Eight percent have amenorrhea. Fluctuations in blood glucose and insulin concentration are probably contributing factors, but the irregular menstrual cycles are mainly caused by disorders in the central ovulatory mechanisms. Hypothalamic GnRH release is regulated by several neuropeptides. Dopamine and opiates exert an inhibitory effect, and there is evidence for an abnormally high dopaminergic hypothalamic activity among women with IDDM. There might also be disorders of the opioid, serotonergic and GABA'ergic systems, but the consequences of there possibilities remain uncertain. Udgivelsesdato: 1994-Oct-17",

keywords = "Diabetes Mellitus, Type 1, Female, Humans, Hypothalamo-Hypophyseal System, Menstruation Disturbances, Ovary",

author = "St{\o}ving, {R K} and J Hangaard and Pedersen, {K K} and C Hagen",

year = "1994",

language = "Dansk",

volume = "156",

pages = "6180--4",

journal = "Ugeskrift for L{\ae}ger",

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publisher = "Almindelige Danske Laegeforening",

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TY - JOUR

T1 - Menstruationsforstyrrelser ved insulinkraevende diabetes mellitus--epidemiologi og årsager

AU - Støving, R K

AU - Hangaard, J

AU - Pedersen, K K

AU - Hagen, C

PY - 1994

Y1 - 1994

N2 - About 20% of all women with insulin-dependent diabetes mellitus (IDDM) have menstrual irregularities. Eight percent have amenorrhea. Fluctuations in blood glucose and insulin concentration are probably contributing factors, but the irregular menstrual cycles are mainly caused by disorders in the central ovulatory mechanisms. Hypothalamic GnRH release is regulated by several neuropeptides. Dopamine and opiates exert an inhibitory effect, and there is evidence for an abnormally high dopaminergic hypothalamic activity among women with IDDM. There might also be disorders of the opioid, serotonergic and GABA'ergic systems, but the consequences of there possibilities remain uncertain. Udgivelsesdato: 1994-Oct-17

AB - About 20% of all women with insulin-dependent diabetes mellitus (IDDM) have menstrual irregularities. Eight percent have amenorrhea. Fluctuations in blood glucose and insulin concentration are probably contributing factors, but the irregular menstrual cycles are mainly caused by disorders in the central ovulatory mechanisms. Hypothalamic GnRH release is regulated by several neuropeptides. Dopamine and opiates exert an inhibitory effect, and there is evidence for an abnormally high dopaminergic hypothalamic activity among women with IDDM. There might also be disorders of the opioid, serotonergic and GABA'ergic systems, but the consequences of there possibilities remain uncertain. Udgivelsesdato: 1994-Oct-17

KW - Diabetes Mellitus, Type 1

KW - Female

KW - Humans

KW - Hypothalamo-Hypophyseal System

KW - Menstruation Disturbances

KW - Ovary

M3 - Tidsskriftartikel

C2 - 7998353

SN - 0041-5782

VL - 156

SP - 6180

EP - 6184

JO - Ugeskrift for Læger

JF - Ugeskrift for Læger

IS - 42

ER -