Medical adherence to topical corticosteroid preparations prescribed for psoriasis

A systematic review

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Resumé

OBJECTIVE: Topical corticosteroids and corticosteroid combinations are the principal treatments in psoriasis. The aim of this study was to investigate published literature dealing with medical adherence to topical corticosteroid or corticosteroid combinations in patients with psoriasis.

MATERIALS AND METHODS: Systematic electronic searches in English language literature were done until September 2015 without publication date restriction.

RESULTS: We identified 11 studies consisting of five surveys, two prospective studies, one qualitative study, one mixed-method study, one register study, and one interventional study. Observation periods varied and rates of nonadherence ranged from 8% to 88.3%. The rates were reported by patients on eight nonvalidated scales and one validated scale, measured by medication weight in two studies, and in two studies rates of nonadherence were measured using prescription registers. Thirty-four multifactorial determinants of nonadherence were found. One designed intervention consisted of a disease management program, which improved adherence in the study period. Overall, the studies included were heterogeneous in design and had a high risk of bias.

CONCLUSION: To improve health outcome in topical treatment of psoriasis, further studies should be conducted addressing determinants of nonadherence and test interventions to improve adherence. Validated measurements of medical nonadherence, prescription registers, or medication-weight are needed.

OriginalsprogEngelsk
TidsskriftJournal of Dermatological Treatment
Vol/bind28
Udgave nummer1
Sider (fra-til)32-39
ISSN0954-6634
DOI
StatusUdgivet - 2017

Fingeraftryk

Psoriasis
Adrenal Cortex Hormones
Prescriptions
Weights and Measures
Disease Management
Publications
Language
Observation
Prospective Studies
Health

Citer dette

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abstract = "OBJECTIVE: Topical corticosteroids and corticosteroid combinations are the principal treatments in psoriasis. The aim of this study was to investigate published literature dealing with medical adherence to topical corticosteroid or corticosteroid combinations in patients with psoriasis.MATERIALS AND METHODS: Systematic electronic searches in English language literature were done until September 2015 without publication date restriction.RESULTS: We identified 11 studies consisting of five surveys, two prospective studies, one qualitative study, one mixed-method study, one register study, and one interventional study. Observation periods varied and rates of nonadherence ranged from 8{\%} to 88.3{\%}. The rates were reported by patients on eight nonvalidated scales and one validated scale, measured by medication weight in two studies, and in two studies rates of nonadherence were measured using prescription registers. Thirty-four multifactorial determinants of nonadherence were found. One designed intervention consisted of a disease management program, which improved adherence in the study period. Overall, the studies included were heterogeneous in design and had a high risk of bias.CONCLUSION: To improve health outcome in topical treatment of psoriasis, further studies should be conducted addressing determinants of nonadherence and test interventions to improve adherence. Validated measurements of medical nonadherence, prescription registers, or medication-weight are needed.",
author = "Svendsen, {Mathias Tiedemann} and Flemming Andersen and Jakob Hansen and Helle Johannessen and Andersen, {Klaus Ejner}",
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Medical adherence to topical corticosteroid preparations prescribed for psoriasis : A systematic review. / Svendsen, Mathias Tiedemann; Andersen, Flemming; Hansen, Jakob; Johannessen, Helle; Andersen, Klaus Ejner.

I: Journal of Dermatological Treatment, Bind 28, Nr. 1, 2017, s. 32-39.

Publikation: Bidrag til tidsskriftReviewForskningpeer review

TY - JOUR

T1 - Medical adherence to topical corticosteroid preparations prescribed for psoriasis

T2 - A systematic review

AU - Svendsen, Mathias Tiedemann

AU - Andersen, Flemming

AU - Hansen, Jakob

AU - Johannessen, Helle

AU - Andersen, Klaus Ejner

PY - 2017

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N2 - OBJECTIVE: Topical corticosteroids and corticosteroid combinations are the principal treatments in psoriasis. The aim of this study was to investigate published literature dealing with medical adherence to topical corticosteroid or corticosteroid combinations in patients with psoriasis.MATERIALS AND METHODS: Systematic electronic searches in English language literature were done until September 2015 without publication date restriction.RESULTS: We identified 11 studies consisting of five surveys, two prospective studies, one qualitative study, one mixed-method study, one register study, and one interventional study. Observation periods varied and rates of nonadherence ranged from 8% to 88.3%. The rates were reported by patients on eight nonvalidated scales and one validated scale, measured by medication weight in two studies, and in two studies rates of nonadherence were measured using prescription registers. Thirty-four multifactorial determinants of nonadherence were found. One designed intervention consisted of a disease management program, which improved adherence in the study period. Overall, the studies included were heterogeneous in design and had a high risk of bias.CONCLUSION: To improve health outcome in topical treatment of psoriasis, further studies should be conducted addressing determinants of nonadherence and test interventions to improve adherence. Validated measurements of medical nonadherence, prescription registers, or medication-weight are needed.

AB - OBJECTIVE: Topical corticosteroids and corticosteroid combinations are the principal treatments in psoriasis. The aim of this study was to investigate published literature dealing with medical adherence to topical corticosteroid or corticosteroid combinations in patients with psoriasis.MATERIALS AND METHODS: Systematic electronic searches in English language literature were done until September 2015 without publication date restriction.RESULTS: We identified 11 studies consisting of five surveys, two prospective studies, one qualitative study, one mixed-method study, one register study, and one interventional study. Observation periods varied and rates of nonadherence ranged from 8% to 88.3%. The rates were reported by patients on eight nonvalidated scales and one validated scale, measured by medication weight in two studies, and in two studies rates of nonadherence were measured using prescription registers. Thirty-four multifactorial determinants of nonadherence were found. One designed intervention consisted of a disease management program, which improved adherence in the study period. Overall, the studies included were heterogeneous in design and had a high risk of bias.CONCLUSION: To improve health outcome in topical treatment of psoriasis, further studies should be conducted addressing determinants of nonadherence and test interventions to improve adherence. Validated measurements of medical nonadherence, prescription registers, or medication-weight are needed.

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