Lung Ultrasound in the Assessment of Pulmonary Complications After Lung Transplantation

Jesper Rømhild Davidsen, Hans Henrik Lawaetz Schultz, Daniel Pilsgaard Henriksen, Martin Iversen, Anna Kalhauge, Jørn Carlsen, Michael Perch, Ole Graumann, Christian B Laursen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

INTRODUCTION:  Lung ultrasound (LUS) has a high diagnostic accuracy for identifying frequent conditions in the post-operative phase after lung transplantation (LTx). This study aimed to investigate the feasibility and clinical ability of LUS to identify pulmonary complications such as pleural effusions and pneumonias in the early postoperative phase after LTx.

METHODS:  A prospective cohort study of lung transplant recipients who consecutively underwent single LTx (SLTx) or double LTx (DLTx) at the National Lung Transplantation Center in Denmark from May 1 to October 31, 2015 was conducted. LUS was performed at four time points corresponding to post-transplant day 3, and weeks 2, 6, and 12 (LUS #1 - 4) to detect and monitor variation in pathological LUS findings over time. Concurrent with LUS #4, a high-resolution computed tomography examination of the thorax (HRCT) was also performed.

RESULTS:  14 patients (1 SLTx/13 DLTx, 7 (50 %) women, mean age: 50.4 years) who had undergone the four prespecified LUS examinations were included. Pleural effusion was the most common condition and most pronounced at post-LTx week 2. Findings consistent with pneumonia increased during week 2 and subsequently decreased. Corresponding to LUS #1, 2, 3, and 4, pleural effusion occurred in 85.7 %, 92.9 %, 85.7 %, and 78.6 %, and pneumonia in 21.4 %, 28.6 %, 14.3 %, and 14.3 %, respectively. HRCT findings at post-LTx week 12 were predominantly presented by unspecific ground glass opacities.

CONCLUSION:  In a post-LTx setting, LUS represents a clinical novelty as a feasible diagnostic and monitoring tool to identify pathological pulmonary complications in the early post-operative phase.

OriginalsprogEngelsk
TidsskriftUltraschall in der Medizin (Stuttgart, Germany : 1980)
ISSN0172-4614
DOI
StatusE-pub ahead of print - 9. nov. 2018

Fingeraftryk

Lung
Pleural Effusion
Denmark
Glass
Cohort Studies
Prospective Studies

Citer dette

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title = "Lung Ultrasound in the Assessment of Pulmonary Complications After Lung Transplantation",
abstract = "INTRODUCTION:  Lung ultrasound (LUS) has a high diagnostic accuracy for identifying frequent conditions in the post-operative phase after lung transplantation (LTx). This study aimed to investigate the feasibility and clinical ability of LUS to identify pulmonary complications such as pleural effusions and pneumonias in the early postoperative phase after LTx.METHODS:  A prospective cohort study of lung transplant recipients who consecutively underwent single LTx (SLTx) or double LTx (DLTx) at the National Lung Transplantation Center in Denmark from May 1 to October 31, 2015 was conducted. LUS was performed at four time points corresponding to post-transplant day 3, and weeks 2, 6, and 12 (LUS #1 - 4) to detect and monitor variation in pathological LUS findings over time. Concurrent with LUS #4, a high-resolution computed tomography examination of the thorax (HRCT) was also performed.RESULTS:  14 patients (1 SLTx/13 DLTx, 7 (50 {\%}) women, mean age: 50.4 years) who had undergone the four prespecified LUS examinations were included. Pleural effusion was the most common condition and most pronounced at post-LTx week 2. Findings consistent with pneumonia increased during week 2 and subsequently decreased. Corresponding to LUS #1, 2, 3, and 4, pleural effusion occurred in 85.7 {\%}, 92.9 {\%}, 85.7 {\%}, and 78.6 {\%}, and pneumonia in 21.4 {\%}, 28.6 {\%}, 14.3 {\%}, and 14.3 {\%}, respectively. HRCT findings at post-LTx week 12 were predominantly presented by unspecific ground glass opacities.CONCLUSION:  In a post-LTx setting, LUS represents a clinical novelty as a feasible diagnostic and monitoring tool to identify pathological pulmonary complications in the early post-operative phase.",
author = "Davidsen, {Jesper R{\o}mhild} and Schultz, {Hans Henrik Lawaetz} and Henriksen, {Daniel Pilsgaard} and Martin Iversen and Anna Kalhauge and J{\o}rn Carlsen and Michael Perch and Ole Graumann and Laursen, {Christian B}",
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doi = "10.1055/a-0783-2466",
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Lung Ultrasound in the Assessment of Pulmonary Complications After Lung Transplantation. / Davidsen, Jesper Rømhild; Schultz, Hans Henrik Lawaetz; Henriksen, Daniel Pilsgaard; Iversen, Martin; Kalhauge, Anna; Carlsen, Jørn; Perch, Michael; Graumann, Ole; Laursen, Christian B.

I: Ultraschall in der Medizin (Stuttgart, Germany : 1980), 09.11.2018.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Lung Ultrasound in the Assessment of Pulmonary Complications After Lung Transplantation

AU - Davidsen, Jesper Rømhild

AU - Schultz, Hans Henrik Lawaetz

AU - Henriksen, Daniel Pilsgaard

AU - Iversen, Martin

AU - Kalhauge, Anna

AU - Carlsen, Jørn

AU - Perch, Michael

AU - Graumann, Ole

AU - Laursen, Christian B

N1 - © Georg Thieme Verlag KG Stuttgart · New York.

PY - 2018/11/9

Y1 - 2018/11/9

N2 - INTRODUCTION:  Lung ultrasound (LUS) has a high diagnostic accuracy for identifying frequent conditions in the post-operative phase after lung transplantation (LTx). This study aimed to investigate the feasibility and clinical ability of LUS to identify pulmonary complications such as pleural effusions and pneumonias in the early postoperative phase after LTx.METHODS:  A prospective cohort study of lung transplant recipients who consecutively underwent single LTx (SLTx) or double LTx (DLTx) at the National Lung Transplantation Center in Denmark from May 1 to October 31, 2015 was conducted. LUS was performed at four time points corresponding to post-transplant day 3, and weeks 2, 6, and 12 (LUS #1 - 4) to detect and monitor variation in pathological LUS findings over time. Concurrent with LUS #4, a high-resolution computed tomography examination of the thorax (HRCT) was also performed.RESULTS:  14 patients (1 SLTx/13 DLTx, 7 (50 %) women, mean age: 50.4 years) who had undergone the four prespecified LUS examinations were included. Pleural effusion was the most common condition and most pronounced at post-LTx week 2. Findings consistent with pneumonia increased during week 2 and subsequently decreased. Corresponding to LUS #1, 2, 3, and 4, pleural effusion occurred in 85.7 %, 92.9 %, 85.7 %, and 78.6 %, and pneumonia in 21.4 %, 28.6 %, 14.3 %, and 14.3 %, respectively. HRCT findings at post-LTx week 12 were predominantly presented by unspecific ground glass opacities.CONCLUSION:  In a post-LTx setting, LUS represents a clinical novelty as a feasible diagnostic and monitoring tool to identify pathological pulmonary complications in the early post-operative phase.

AB - INTRODUCTION:  Lung ultrasound (LUS) has a high diagnostic accuracy for identifying frequent conditions in the post-operative phase after lung transplantation (LTx). This study aimed to investigate the feasibility and clinical ability of LUS to identify pulmonary complications such as pleural effusions and pneumonias in the early postoperative phase after LTx.METHODS:  A prospective cohort study of lung transplant recipients who consecutively underwent single LTx (SLTx) or double LTx (DLTx) at the National Lung Transplantation Center in Denmark from May 1 to October 31, 2015 was conducted. LUS was performed at four time points corresponding to post-transplant day 3, and weeks 2, 6, and 12 (LUS #1 - 4) to detect and monitor variation in pathological LUS findings over time. Concurrent with LUS #4, a high-resolution computed tomography examination of the thorax (HRCT) was also performed.RESULTS:  14 patients (1 SLTx/13 DLTx, 7 (50 %) women, mean age: 50.4 years) who had undergone the four prespecified LUS examinations were included. Pleural effusion was the most common condition and most pronounced at post-LTx week 2. Findings consistent with pneumonia increased during week 2 and subsequently decreased. Corresponding to LUS #1, 2, 3, and 4, pleural effusion occurred in 85.7 %, 92.9 %, 85.7 %, and 78.6 %, and pneumonia in 21.4 %, 28.6 %, 14.3 %, and 14.3 %, respectively. HRCT findings at post-LTx week 12 were predominantly presented by unspecific ground glass opacities.CONCLUSION:  In a post-LTx setting, LUS represents a clinical novelty as a feasible diagnostic and monitoring tool to identify pathological pulmonary complications in the early post-operative phase.

U2 - 10.1055/a-0783-2466

DO - 10.1055/a-0783-2466

M3 - Journal article

C2 - 30414162

JO - Ultraschall in der Medizin

JF - Ultraschall in der Medizin

SN - 0172-4614

ER -