Levels of Circulating MMCN-151, a Degradation Product of Mimecan, Reflect Pathological Extracellular Matrix Remodeling in Apolipoprotein E Knockout Mice

N Barascuk; E Vassiliadis; Qiuju Zheng; Yu Wang; W Wang; L Larsen; L M Rasmussen; M A Karsdal

doi:10.4137/BMI.S7777

Levels of Circulating MMCN-151, a Degradation Product of Mimecan, Reflect Pathological Extracellular Matrix Remodeling in Apolipoprotein E Knockout Mice

N Barascuk
, E Vassiliadis
, Qiuju Zheng
, Yu Wang
, W Wang
, L Larsen
, L M Rasmussen
, M A Karsdal

Nordic Bioscience

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

Arterial extracellular matrix (ECM) remodeling by matrix metalloproteinases (MMPs) is one of the major hallmarks of atherosclerosis. Mimecan, also known as osteoglycin has been implicated in the integrity of the ECM. This study assessed the validity of an enzyme-linked immunosorbent assay (ELISA) developed to measure a specific MMP12-derived fragment of mimecan, MMCN-151, in apolipoprotein-E knockout (ApoE-KO) mice.

Originalsprog	Engelsk
Tidsskrift	Biomarker Insights
Vol/bind	6
Sider (fra-til)	97-106
Antal sider	10
ISSN	1177-2719
DOI	https://doi.org/10.4137/BMI.S7777
Status	Udgivet - 2011

Dokumenter og links

10.4137/BMI.S7777

SDU link

Tjek adgangen til materialet i Syddansk Universitetsbiblioteks søgemaskine

Citationsformater

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title = "Levels of Circulating MMCN-151, a Degradation Product of Mimecan, Reflect Pathological Extracellular Matrix Remodeling in Apolipoprotein E Knockout Mice",

abstract = "Arterial extracellular matrix (ECM) remodeling by matrix metalloproteinases (MMPs) is one of the major hallmarks of atherosclerosis. Mimecan, also known as osteoglycin has been implicated in the integrity of the ECM. This study assessed the validity of an enzyme-linked immunosorbent assay (ELISA) developed to measure a specific MMP12-derived fragment of mimecan, MMCN-151, in apolipoprotein-E knockout (ApoE-KO) mice.",

author = "N Barascuk and E Vassiliadis and Qiuju Zheng and Yu Wang and W Wang and L Larsen and Rasmussen, \{L M\} and Karsdal, \{M A\}",

year = "2011",

doi = "10.4137/BMI.S7777",

language = "English",

volume = "6",

pages = "97--106",

journal = "Biomarker Insights",

issn = "1177-2719",

publisher = "Libertas Academica Ltd.",

}

TY - JOUR

T1 - Levels of Circulating MMCN-151, a Degradation Product of Mimecan, Reflect Pathological Extracellular Matrix Remodeling in Apolipoprotein E Knockout Mice

AU - Barascuk, N

AU - Vassiliadis, E

AU - Zheng, Qiuju

AU - Wang, Yu

AU - Wang, W

AU - Larsen, L

AU - Rasmussen, L M

AU - Karsdal, M A

PY - 2011

Y1 - 2011

N2 - Arterial extracellular matrix (ECM) remodeling by matrix metalloproteinases (MMPs) is one of the major hallmarks of atherosclerosis. Mimecan, also known as osteoglycin has been implicated in the integrity of the ECM. This study assessed the validity of an enzyme-linked immunosorbent assay (ELISA) developed to measure a specific MMP12-derived fragment of mimecan, MMCN-151, in apolipoprotein-E knockout (ApoE-KO) mice.

AB - Arterial extracellular matrix (ECM) remodeling by matrix metalloproteinases (MMPs) is one of the major hallmarks of atherosclerosis. Mimecan, also known as osteoglycin has been implicated in the integrity of the ECM. This study assessed the validity of an enzyme-linked immunosorbent assay (ELISA) developed to measure a specific MMP12-derived fragment of mimecan, MMCN-151, in apolipoprotein-E knockout (ApoE-KO) mice.

U2 - 10.4137/BMI.S7777

DO - 10.4137/BMI.S7777

M3 - Journal article

C2 - 22084568

SN - 1177-2719

VL - 6

SP - 97

EP - 106

JO - Biomarker Insights

JF - Biomarker Insights

ER -

Levels of Circulating MMCN-151, a Degradation Product of Mimecan, Reflect Pathological Extracellular Matrix Remodeling in Apolipoprotein E Knockout Mice

Abstract

Dokumenter og links

SDU link

Fingeraftryk

Citationsformater