Letter to Editor: Response to AASLD Editorial/Message from the President

Ronald L. Koretz, Janus C. Jakobsen, Goran Hauser, Dimitrinka Nikolova, Christian Gluud

Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

Abstrakt

A commentary [1] criticized our systematic review regarding the use of direct-acting agents (DAAs) in chronic hepatitis C [2]. The following represents our major disagreements. Sustained virological response (SVR) is a non-validated surrogate outcome. The principles of evidence-based medicine require that it be validated in randomized clinical trials (RCTs) by showing parallel benefits in clinical outcomes [3]. This article is protected by copyright. All rights reserved.

OriginalsprogEngelsk
TidsskriftHepatology
Vol/bind69
Udgave nummer5
Sider (fra-til)2300
Antal sider1
ISSN0270-9139
DOI
StatusUdgivet - maj 2019

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