Large porcine model of profound acute ischemic cardiogenic shock

Ole K. Møller-Helgestad*, Hanne B. Ravn, Jacob E. Møller

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Abstrakt

Cardiogenic shock is one of the leading causes of death following acute myocardial infarction affecting 10% of patients with large myocardial infarcts with a subsequent mortality rate of 50%. Here we describe a large porcine model of acute ischemic cardiogenic shock. Acute left or right ventricular failure can be achieved with close to a 100% success rate by stepwise injection of microspheres into the left or right coronary artery, respectively, and the method allows for titration of heart failure to a prespecified level.

OriginalsprogEngelsk
TitelExperimental Models of Cardiovascular Diseases
RedaktørerKiyotake Ishikawa
ForlagHumana Press
Publikationsdato2018
Sider343-352
Kapitel27
ISBN (Trykt)9781493985968
ISBN (Elektronisk)9781493985975
DOI
StatusUdgivet - 2018
NavnMethods in Molecular Biology
Vol/bind1816
ISSN1064-3745

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Citationsformater

Møller-Helgestad, O. K., Ravn, H. B., & Møller, J. E. (2018). Large porcine model of profound acute ischemic cardiogenic shock. I K. Ishikawa (red.), Experimental Models of Cardiovascular Diseases (s. 343-352). Humana Press. Methods in Molecular Biology, Bind. 1816 https://doi.org/10.1007/978-1-4939-8597-5_27