Laboratoriediagnostik af infektion forårsaget af Borrelia burgdorferi

Ram B Dessau; Jette M Bangsborg; Tove P Ejlertsen Jensen; Klaus Hansen; Anne-Mette K Lebech; Christian Østergaard Andersen

Laboratoriediagnostik af infektion forårsaget af Borrelia burgdorferi

Ram B Dessau, Jette M Bangsborg, Tove P Ejlertsen Jensen, Klaus Hansen, Anne-Mette K Lebech, Christian Østergaard Andersen

IRS - Næstved, Slagelse, Ringsted Sygehuse (NSR)

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstrakt

The laboratory diagnosis of Lyme disease in Denmark is reviewed with recommendations for serological testing. In Denmark the laboratory testing is performed with an ELISA technique. Most laboratories use an assay based on purified flagella antigen. The two-tier approach with Western Blot as confirmatory testing is not recommended since the contribution to the diagnostic specificity is only marginal. Predictive values of Lyme serology are presented, based on the estimated prevalence of the different stages of Lyme disease in Denmark.

Bidragets oversatte titel	Laboratory diagnosis of infection caused by Borrelia burgdorferi
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Læger
Vol/bind	168
Udgave nummer	34
Sider (fra-til)	2805-2807
ISSN	0041-5782
Status	Udgivet - 21. aug. 2006

Emneord

Antibodies, Bacterial
Blotting, Western
Borrelia burgdorferi
Enzyme-Linked Immunosorbent Assay
Humans
Lyme Disease
Lyme Neuroborreliosis
Serologic Tests

Citationsformater

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abstract = "The laboratory diagnosis of Lyme disease in Denmark is reviewed with recommendations for serological testing. In Denmark the laboratory testing is performed with an ELISA technique. Most laboratories use an assay based on purified flagella antigen. The two-tier approach with Western Blot as confirmatory testing is not recommended since the contribution to the diagnostic specificity is only marginal. Predictive values of Lyme serology are presented, based on the estimated prevalence of the different stages of Lyme disease in Denmark.",

keywords = "Antibodies, Bacterial, Blotting, Western, Borrelia burgdorferi, Enzyme-Linked Immunosorbent Assay, Humans, Lyme Disease, Lyme Neuroborreliosis, Serologic Tests",

author = "Dessau, {Ram B} and Bangsborg, {Jette M} and Jensen, {Tove P Ejlertsen} and Klaus Hansen and Lebech, {Anne-Mette K} and Andersen, {Christian {\O}stergaard}",

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TY - JOUR

T1 - Laboratoriediagnostik af infektion forårsaget af Borrelia burgdorferi

AU - Dessau, Ram B

AU - Bangsborg, Jette M

AU - Jensen, Tove P Ejlertsen

AU - Hansen, Klaus

AU - Lebech, Anne-Mette K

AU - Andersen, Christian Østergaard

PY - 2006/8/21

Y1 - 2006/8/21

N2 - The laboratory diagnosis of Lyme disease in Denmark is reviewed with recommendations for serological testing. In Denmark the laboratory testing is performed with an ELISA technique. Most laboratories use an assay based on purified flagella antigen. The two-tier approach with Western Blot as confirmatory testing is not recommended since the contribution to the diagnostic specificity is only marginal. Predictive values of Lyme serology are presented, based on the estimated prevalence of the different stages of Lyme disease in Denmark.

AB - The laboratory diagnosis of Lyme disease in Denmark is reviewed with recommendations for serological testing. In Denmark the laboratory testing is performed with an ELISA technique. Most laboratories use an assay based on purified flagella antigen. The two-tier approach with Western Blot as confirmatory testing is not recommended since the contribution to the diagnostic specificity is only marginal. Predictive values of Lyme serology are presented, based on the estimated prevalence of the different stages of Lyme disease in Denmark.

KW - Antibodies, Bacterial

KW - Blotting, Western

KW - Borrelia burgdorferi

KW - Enzyme-Linked Immunosorbent Assay

KW - Humans

KW - Lyme Disease

KW - Lyme Neuroborreliosis

KW - Serologic Tests

M3 - Tidsskriftartikel

C2 - 16942701

SN - 0041-5782

VL - 168

SP - 2805

EP - 2807

JO - Ugeskrift for Læger

JF - Ugeskrift for Læger

IS - 34

ER -

Laboratoriediagnostik af infektion forårsaget af Borrelia burgdorferi

Abstrakt

Emneord

Fingeraftryk

Citationsformater