Kidney disease cohort (KidDiCo) of southern Denmark: Design, coverage, generalizability and implications for use

Jan Dominik Kampmann*, James Goya Heaf, Christian Backer Mogensen, Hans Mickley, Frans Brandt

*Kontaktforfatter for dette arbejde

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

15 Downloads (Pure)

Abstrakt

Background: This article provides a description of a large register of a population from the Region of Southern Denmark, the Kidney Disease Cohort (KiDiCo). Coverage and representativeness according to gender and education level are discussed. Methods: Data for KiDiCo were obtained using laboratory databases from participating laboratories in the Region of Southern Denmark and were linked to individual personal 10-digit personal identification numbers. The study population includes individuals over 18 years of age living in Denmark, whose serum creatinine was analysed in one of the 27 participating laboratories in the Region of Southern Denmark during the period of 8 years from 1st January 2006 to 31st December 2013. Individually linked data consist of diagnosis codes, date and cause of death, dispensed medicine data, socioeconomic data and demographic data. Results: In total, n = 669,929 individuals had their blood tested for creatinine between 2007 and 2013 in a defined geographical area. The estimated geographical coverage was 78%. The median age of the background population was 6 years lower. The cohort had a slightly higher percentage of females (53%) compared to the background population (49%). Differences in educational levels reflect the minor age gap. Conclusion: Based on coverage of 78% together with similar characteristics in terms of gender and age, the KiDiCo is a representative cohort of patients in the Region of Southern Denmark. Combining laboratory data with high-quality Danish administrative registers makes diverse research feasible.

OriginalsprogEngelsk
TidsskriftClinical Epidemiology
Vol/bind13
Sider (fra-til)971-980
ISSN1179-1349
DOI
StatusUdgivet - 2021

Bibliografisk note

Funding Information:
This work was supported by the University of Southern Denmark, the Region of Southern Denmark, Hospital of Southern Jutland and Knud and Edith Erichsen’s Fund. We would like to thank Jan Hellden, Jens Hastrup, Donna Lykke Wolf and Eithne Hayes Bauer.

Publisher Copyright:
© 2021 Kampmann et al.

Fingeraftryk

Dyk ned i forskningsemnerne om 'Kidney disease cohort (KidDiCo) of southern Denmark: Design, coverage, generalizability and implications for use'. Sammen danner de et unikt fingeraftryk.

Citationsformater