Purpose: To provide complete and validated data on mortality after cardiac implantable electronic device (CIED) procedures, including pacemakers (PM), cardiac resynchronization therapy devices with defibrillator (CRT-D) or without (CRT-P), and implantable cardioverter defibrillators (ICD). Furthermore, to assess association between early reoperation - and other possible predictors - and all-cause mortality. Methods: A nationwide cohort study was performed including all patients who underwent a CIED procedure in Denmark from May 1 2010 to April 30 2011. Data on reoperations due to a complication were based on an active review of all patient charts while baseline data came from the Danish Pacemaker and ICD Register. Study outcome was 6 months all-cause mortality. Adjusted hazard ratios (aHR) with 95% confidence intervals (CI) were estimated using Cox proportional hazards regression. Early reoperation was entered as a time dependent covariate. Results: The study population consisted of 5,918 consecutive patients; PM: n=4,189, CRT-P: n=209, ICD: n=1,075, CRT-D: n=445. A total of 327 patients (5.5%) died within the first 6 months. No patients died as a direct result of a procedure related complication. We found no significant association between early reoperation and 6 months mortality (aHR 1.6; 95% CI 0.9-3.0), Figure. Mortality was higher if the patient was underweight (aHR 2.6; 95% CI 1.8-3.8), received a single-lead PM (a HR 2.7; 95% CI 2.1- 3.5), or had medium (aHR 1.7; 95% CI 1.2-2.6) or high (aHR 4.0; 95% CI 2.8-5.8) Charlson comorbidity score. We found no association between annual operator volume and mortality. Conclusions: No association was found between early reoperation due to a complication and 6-months all-cause mortality. (Figure Presented).
|Status||Udgivet - 2015|
|Begivenhed||EHRA EUROPACE 2015 - Milano , Italien|
Varighed: 21. jun. 2015 → 24. jun. 2015
|Konference||EHRA EUROPACE 2015|
|Periode||21/06/2015 → 24/06/2015|
- *procedures *mortality *Denmark *reoperation human patient pacemaker defibrillator cohort analysis cardiac resynchronization therapy device implantable cardioverter defibrillator proportional hazards model population register hazard ratio confidence interval underweight Charlson Comorbidity Index devices