Intratumoral Heterogeneity in Cancer/testis Antigen Expression in Solid Tumors, Implications for Cancer Immunotherapy

Mie Killerich Jakobsen

Publikation: Afhandling › Ph.d.-afhandling

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2025
Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition
Jakobsen, M. K., Traynor, S., Nielsen, A. Y., Dahl, C., Staehr, M., Jakobsen, S. T., Madsen, M. S., Siersbaek, R., Terp, M. G., Jensen, J. B., Pedersen, C. B., Shrestha, A., Brewer, J. R., Duijf, P. H. G., Gammelgaard, O. L., Ditzel, H. J., Kirkin, A. F., Guldberg, P. & Gjerstorff, M. F., 23. jan. 2025, I: Journal of Experimental & Clinical Cancer Research. 44, 1, 15 s., 21.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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2024
Single-cell sequencing unveils extensive intratumoral heterogeneity of cancer/testis antigen expression in melanoma and lung cancer
Traynor, S., Jakobsen, M. K., Green, T. M., Komic, H., Palarasah, Y., Pedersen, C. B., Ditzel, H. J., Thoren, F. B., Guldberg, P. & Gjerstorff, M. F., 17. jun. 2024, I: Journal for ImmunoTherapy of Cancer. 12, 6, 9 s., e008759.
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2021
The Cancer/Testis Antigen Gene VCX2 Is Rarely Expressed in Malignancies but Can Be Epigenetically Activated Using DNA Methyltransferase and Histone Deacetylase Inhibitors
Jakobsen, M. K., Traynor, S., Stæhr, M., Duijf, P. G., Nielsen, A. Y., Terp, M. G., Pedersen, C. B., Guldberg, P., Ditzel, H. J. & Gjerstorff, M. F., 9. feb. 2021, I: Frontiers in Oncology. 10, 12 s., 584024.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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