INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF

Erik Bjerregaard Pedersen (Opfinder), Amany Mostafa Ahmed Osman (Opfinder), Per Trolle Jørgensen (Opfinder), Niels Bomholt (Opfinder)

Publikation: Patent

Abstrakt

There is provided an intercalating oligonucleotide for stabilizing natural or modified DNA and RNA triplexes, duplexes and hybrids thereof having the general structure (I) triplex forming oligonucleotides of the invention are capable of binding specifically to double stranded target nucleic acids and are therefore of interest for modulation of the activity of target nucleic acids and also detection of target nucleic acids.
OriginalsprogEngelsk
PatentnummerWO2009135890
Journaliseringsdato12/11/2009
LandDanmark
StatusUdgivet - 2009

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