Influence of post discharge nutrition on body composition at 6 years of age among children born very preterm

Bidragets oversatte titel: Den tidlige ernærings indflydelse på kropssammensætning hos 6 årige børn født meget prætermt.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review


Background Very preterm born infants receive nutrition that ensures optimal growth during the neonatal period. New research has shown that the type of nutrition in early life may affect not only growth but also later body composition and risk of developing metabolic syndrome. Aim • To evaluate if type of nutrition in early life effects the body composition in later life among very preterm born children Method In 2004-08 a birth cohort of very preterm born infants with a gestational age ≤32+0 weeks. At time of hospital discharge, the infants were randomised into 3 different feeding groups. If possible to breastfeed, the infant was randomised to one of two groups • Breastfeeding solely (human milk) • Breastfeeding enriched with fortification (human milk fortifier) If breastfeeding was not possible the infant received • Preterm formula. They were all fed the specific nutrition from discharge to 4 month corrected age. At 6 years, a dexa scan was performed to evaluate body composition. Results A total number of 277 infants will be invited to follow up at 6 years of age. So far 79 children have had a dexa scan performed (HM 26, HMF: 22 and PF: 31). Fat mass (FM) and muscle mass (MM) was measured. Fat mass in both the HMF and PF groups was higher compared to the HM group (p<0, 05) and (p<0, 02) respectively. Fat mass in PF was not significantly higher compared to HMF. (Figure 1) Muscle mass was almost similar in the HM (16.633 g) and PF groups (16.310 g) and both higher than the HMF group (15.841 g), but no significant difference between the groups. Conclusion Human milk seems to result in a lower fat mass and higher muscle mass among very preterm born infants. The results are preliminary due to the small number of children. The remaining children in this cohort will be invited to similar investigations when reaching their 6 years birthday.
Bidragets oversatte titelDen tidlige ernærings indflydelse på kropssammensætning hos 6 årige børn født meget prætermt.
Publikationsdato30. jan. 2014
Antal sider1
StatusUdgivet - 30. jan. 2014
Begivenhed2nd International Conference on Nutrition & Growth - Barcelona, Spanien
Varighed: 30. jan. 20141. feb. 2014
Konferencens nummer: 2


Konference2nd International Conference on Nutrition & Growth


  • Neonates
  • Nutrition
  • Body composition
  • Nutrition and growth

    Line Hedegaard Toftlund (Deltager)

    30. jan. 20142. feb. 2014

    Aktivitet: Deltagelse i faglig begivenhedOrganisering af eller deltagelse i konference