Objective: To examine whether the association between birth weight and fat distribution in childhood is modified by parental overweight. Methods: Cross-sectional study of 728 Danish children aged 8-10 and 14-16 years. The main outcomes were waist circumference, waist-to-height ratio, subscapular skinfold, and subscapular-to-triceps skinfold ratio. Analyses were stratified by parental overweight status (none vs. ≥1 overweight parent) for each dependent variable, expressed as z-scores. Results: Birth weight z-score was negatively associated with waist circumference (β -0.08 SD; 95% CI -0.15, -0.02), waist-to-height ratio (β -0.15 SD; 95% CI -0.22, -0.07), and subscapular-to-triceps ratio (β -0.28 SD; 95% CI -0.44, -0.12) after adjustment for sex, age, puberty, preterm birth, BMI, height, socio-economic status, mother's age at delivery, parity, breastfeeding, energy intake, and aerobic fitness in the group with ≥1 overweight parent. Birth weight was negatively associated with subscapular skinfold in groups with (β -0.16 SD; 95% CI -0.24, -0.06) and without overweight parents (β -0.09 SD; 95% CI -0.16, -0.02), but the magnitude of the association was greater in the former group. Conclusion: The association between birth weight and fat distribution seems to be influenced by parental overweight. Lower birth weights are associated with central adiposity among offspring of overweight parents. Copyright © 2012 S. Karger GmbH, Freiburg.
Bibliografisk notePublished Online: October 27, 2012
Adegboye, A. R. A., Andersen, L. B., Wedderkopp, N., & Heitmann, B. L. (2012). Influence of Parental Overweight on the Association of Birth Weight and Fat Distribution Later in Childhood. Obesity Facts, 5(5), 784-794. https://doi.org/10.1159/000343916