Infektioner og hjerte-kar-sygdomme, H:S IAMA gruppen

H J Kolmos, Christian Nyfeldt Gluud

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

Epidemiological studies indicate that respiratory tract and dental infections increase the risk of atherosclerotic cardiovascular disease. Several microorganisms have been claimed as clinically important, especially Chlamydia pneumoniae (Cp) and cytomegalovirus (CMV), Cp is frequently isolated from atherosclerotic plaques, and treatment with macrolide antibiotics may have a beneficial effect on the course of ischaemic heart disease. CMV seems to play a role in the development of coronary stenosis following coronary bypass surgery and heart transplantation. Likewise, inflammatory markers are associated with atherosclerotic cardiovascular disease. The pathogenetic role of microorganisms may be ascribed to the inflammatory response, which is elicited during infection. There is an urgent need for more documentation of the role of microorganisms in cardiovascular disease, and of the possible clinical effect of antibiotic treatment.

Bidragets oversatte titelInfections and cardiovascular disease
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind161
Udgave nummer37
Sider (fra-til)5161-4
Antal sider4
ISSN0041-5782
StatusUdgivet - 13. sep. 1999
Udgivet eksterntJa

Emneord

  • Anti-Bacterial Agents
  • Arteriosclerosis
  • Coronary Artery Disease
  • Coronary Disease
  • Humans
  • Oral Health
  • Periodontitis
  • Randomized Controlled Trials as Topic
  • Respiratory Tract Infections
  • Risk Factors

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