Individual levels of plasma histidine-rich glycoprotein (HRG) during the normal menstrual cycle and in women on oral contraceptives low in oestrogen

Jørgen Jespersen*, Cornelis Kluft

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Abstrakt

Histidine-rich glycoprotein (HRG), a 3.8 S-α2-glycoprotein recently identified as a new fibrinolysis regulating protein, was determined by an electroimmunoassay in samples of plasma collected during one menstrual or hormone cycle in 15 young women and in 11 women using oral contraceptives with 30 μethinyl oestradiol and 150 μ levo-norgestrel. Distinct individual levels caused the within-group variations of plasma HRG to be larger than the individual variations. In the hormone group the plasma HRG levels were decreased to about 75% of the normal, while the fluctuations during the cycle were minor in both groups.

OriginalsprogEngelsk
BogserieScandinavian Journal of Clinical and Laboratory Investigation
Vol/bind42
Udgave nummer7
Sider (fra-til)563-566
Antal sider4
ISSN0036-5513
DOI
StatusUdgivet - 1982

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