Independent associations of physical activity and cardiorespiratory fitness with metabolic risk factors in children: the European youth heart study

U Ekelund, S A Anderssen, K Froberg, L B Sardinha, L B Andersen, S Brage, Youth Heart Study Group European

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Udgivelsesdato: september
OriginalsprogEngelsk
TidsskriftDiabetologia
Vol/bind50
Udgave nummer9
Sider (fra-til)1832-1840
Antal sider8
ISSN0012-186X
DOI
StatusUdgivet - 1. sep. 2007

Fingeraftryk

Exercise
Adiposity
Cardiorespiratory Fitness
HDL Cholesterol
Fasting
Cross-Sectional Studies
Insulin
Population

Citer dette

Ekelund, U ; Anderssen, S A ; Froberg, K ; Sardinha, L B ; Andersen, L B ; Brage, S ; European, Youth Heart Study Group. / Independent associations of physical activity and cardiorespiratory fitness with metabolic risk factors in children: the European youth heart study. I: Diabetologia. 2007 ; Bind 50, Nr. 9. s. 1832-1840.
@article{bdb81410eab511dc86ef000ea68e967b,
title = "Independent associations of physical activity and cardiorespiratory fitness with metabolic risk factors in children: the European youth heart study",
abstract = "AIMS/HYPOTHESIS: High levels of cardiorespiratory fitness (CRF) and physical activity (PA) are associated with a favourable metabolic risk profile. However, there has been no thorough exploration of the independent contributions of cardiorespiratory fitness and subcomponents of activity (total PA, time spent sedentary, and time spent in light, moderate and vigorous intensity PA) to metabolic risk factors in children and the relative importance of these factors. METHODS: We performed a population-based, cross-sectional study in 9- to 10- and 15- to 16-year-old boys and girls from three regions of Europe (n = 1709). We examined the independent associations of subcomponents of PA and CRF with metabolic risk factors (waist circumference, BP, fasting glucose, insulin, triacylglycerol and HDL-cholesterol levels). Clustered metabolic risk was expressed as a continuously distributed score calculated as the average of the standardised values of the six subcomponents. RESULTS: CRF (standardised beta = -0.09, 95{\%} CI -0.12, -0.06), total PA (standardised beta = -0.08, 95{\%} CI -0.10, -0.05) and all other subcomponents of PA were significantly associated with clustered metabolic risk. After excluding waist circumference from the summary score and further adjustment for waist circumference as a confounding factor, the magnitude of the association between CRF and clustered metabolic risk was attenuated (standardised beta = -0.05, 95{\%} CI -0.08, -0.02), whereas the association with total PA was unchanged (standardised beta = -0.08 95{\%} CI -0.10, -0.05). CONCLUSIONS/INTERPRETATION: PA and CRF are separately and independently associated with individual and clustered metabolic risk factors in children. The association between CRF and clustered risk is partly mediated or confounded by adiposity, whereas the association between activity and clustered risk is independent of adiposity. Our results suggest that fitness and activity affect metabolic risk through different pathways.",
keywords = "Adolescent, Body Mass Index, Child, Cross-Sectional Studies, Europe, Female, Heart, Humans, Male, Motor Activity, Physical Fitness, Respiratory Physiology, Risk Factors, Smoking",
author = "U Ekelund and Anderssen, {S A} and K Froberg and Sardinha, {L B} and Andersen, {L B} and S Brage and European, {Youth Heart Study Group}",
year = "2007",
month = "9",
day = "1",
doi = "10.1007/s00125-007-0762-5",
language = "English",
volume = "50",
pages = "1832--1840",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Heinemann",
number = "9",

}

Independent associations of physical activity and cardiorespiratory fitness with metabolic risk factors in children: the European youth heart study. / Ekelund, U; Anderssen, S A; Froberg, K; Sardinha, L B; Andersen, L B; Brage, S; European, Youth Heart Study Group.

I: Diabetologia, Bind 50, Nr. 9, 01.09.2007, s. 1832-1840.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Independent associations of physical activity and cardiorespiratory fitness with metabolic risk factors in children: the European youth heart study

AU - Ekelund, U

AU - Anderssen, S A

AU - Froberg, K

AU - Sardinha, L B

AU - Andersen, L B

AU - Brage, S

AU - European, Youth Heart Study Group

PY - 2007/9/1

Y1 - 2007/9/1

N2 - AIMS/HYPOTHESIS: High levels of cardiorespiratory fitness (CRF) and physical activity (PA) are associated with a favourable metabolic risk profile. However, there has been no thorough exploration of the independent contributions of cardiorespiratory fitness and subcomponents of activity (total PA, time spent sedentary, and time spent in light, moderate and vigorous intensity PA) to metabolic risk factors in children and the relative importance of these factors. METHODS: We performed a population-based, cross-sectional study in 9- to 10- and 15- to 16-year-old boys and girls from three regions of Europe (n = 1709). We examined the independent associations of subcomponents of PA and CRF with metabolic risk factors (waist circumference, BP, fasting glucose, insulin, triacylglycerol and HDL-cholesterol levels). Clustered metabolic risk was expressed as a continuously distributed score calculated as the average of the standardised values of the six subcomponents. RESULTS: CRF (standardised beta = -0.09, 95% CI -0.12, -0.06), total PA (standardised beta = -0.08, 95% CI -0.10, -0.05) and all other subcomponents of PA were significantly associated with clustered metabolic risk. After excluding waist circumference from the summary score and further adjustment for waist circumference as a confounding factor, the magnitude of the association between CRF and clustered metabolic risk was attenuated (standardised beta = -0.05, 95% CI -0.08, -0.02), whereas the association with total PA was unchanged (standardised beta = -0.08 95% CI -0.10, -0.05). CONCLUSIONS/INTERPRETATION: PA and CRF are separately and independently associated with individual and clustered metabolic risk factors in children. The association between CRF and clustered risk is partly mediated or confounded by adiposity, whereas the association between activity and clustered risk is independent of adiposity. Our results suggest that fitness and activity affect metabolic risk through different pathways.

AB - AIMS/HYPOTHESIS: High levels of cardiorespiratory fitness (CRF) and physical activity (PA) are associated with a favourable metabolic risk profile. However, there has been no thorough exploration of the independent contributions of cardiorespiratory fitness and subcomponents of activity (total PA, time spent sedentary, and time spent in light, moderate and vigorous intensity PA) to metabolic risk factors in children and the relative importance of these factors. METHODS: We performed a population-based, cross-sectional study in 9- to 10- and 15- to 16-year-old boys and girls from three regions of Europe (n = 1709). We examined the independent associations of subcomponents of PA and CRF with metabolic risk factors (waist circumference, BP, fasting glucose, insulin, triacylglycerol and HDL-cholesterol levels). Clustered metabolic risk was expressed as a continuously distributed score calculated as the average of the standardised values of the six subcomponents. RESULTS: CRF (standardised beta = -0.09, 95% CI -0.12, -0.06), total PA (standardised beta = -0.08, 95% CI -0.10, -0.05) and all other subcomponents of PA were significantly associated with clustered metabolic risk. After excluding waist circumference from the summary score and further adjustment for waist circumference as a confounding factor, the magnitude of the association between CRF and clustered metabolic risk was attenuated (standardised beta = -0.05, 95% CI -0.08, -0.02), whereas the association with total PA was unchanged (standardised beta = -0.08 95% CI -0.10, -0.05). CONCLUSIONS/INTERPRETATION: PA and CRF are separately and independently associated with individual and clustered metabolic risk factors in children. The association between CRF and clustered risk is partly mediated or confounded by adiposity, whereas the association between activity and clustered risk is independent of adiposity. Our results suggest that fitness and activity affect metabolic risk through different pathways.

KW - Adolescent

KW - Body Mass Index

KW - Child

KW - Cross-Sectional Studies

KW - Europe

KW - Female

KW - Heart

KW - Humans

KW - Male

KW - Motor Activity

KW - Physical Fitness

KW - Respiratory Physiology

KW - Risk Factors

KW - Smoking

U2 - 10.1007/s00125-007-0762-5

DO - 10.1007/s00125-007-0762-5

M3 - Journal article

VL - 50

SP - 1832

EP - 1840

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 9

ER -