Resumé

Background: Obese women undergoing caesarean section are at increased risk of surgical wound complications, which may lead to delayed recovery, pain, reduced quality of life, and increased health care cost. The aim of this study is to evaluate the effect of incisional Negative Pressure Wound Therapy (iNPWT) applied prophylactically following caesarean section compared with standard postoperative dressings in obese women undergoing caesarean section.
Method: This study is designed as an unblinded, pragmatic, parallel randomised multicenter trial, with a 1:1 allocation. A computer random number generator are used to allocate the participants into one of two groups (iNPWT vs. standard dressing), stratified by centre and type of CS. The study is conducted at five public hospitals located in three regions of Denmark. Interim analyses will be preformed along the trial using the group sequential method. The analyses will be performed when sample size reaches 179, 357, 535, 713, and 891, respectively.
Population: women with a pre-gestational BMI ≥ 30 undergoing planned or emergency caesarean section. The iNPWT or standard dressings is applied immediately following operation. In the intervention group the therapy will be left in situ for five days. In the control group the dressing will be left in situ for at least 24 hours as standard procedure. Follow-up is 30 days.
Results: The study is on going. The first 179 participants are about to be analysed. Overall we expect to find a 50% reduction of wound infection when using iNPWT compared to standard postoperative dressings in this high-risk subpopulation.
OriginalsprogEngelsk
Publikationsdato27. aug. 2015
StatusUdgivet - 27. aug. 2015
Begivenhed2nd Nordic Congress on Obesity in Gynaecology and Obstetrics - Hindsgavl Conference Center, Middelfart, Danmark
Varighed: 27. aug. 201529. aug. 2015
Konferencens nummer: 2

Konference

Konference2nd Nordic Congress on Obesity in Gynaecology and Obstetrics
Nummer2
LokationHindsgavl Conference Center
LandDanmark
ByMiddelfart
Periode27/08/201529/08/2015

Emneord

  • Negative Pressure Wound Therapy
  • Randomised Control Trials
  • Obesity
  • Caesarean Section

Citer dette

@conference{10e60381d8cf4dfba255dd7860c28031,
title = "Incisional Negative Pressure Wound Therapy: Metod to reduce the risk of wound infection in obese women following caesarean section",
abstract = "Background: Obese women undergoing caesarean section are at increased risk of surgical wound complications, which may lead to delayed recovery, pain, reduced quality of life, and increased health care cost. The aim of this study is to evaluate the effect of incisional Negative Pressure Wound Therapy (iNPWT) applied prophylactically following caesarean section compared with standard postoperative dressings in obese women undergoing caesarean section.Method: This study is designed as an unblinded, pragmatic, parallel randomised multicenter trial, with a 1:1 allocation. A computer random number generator are used to allocate the participants into one of two groups (iNPWT vs. standard dressing), stratified by centre and type of CS. The study is conducted at five public hospitals located in three regions of Denmark. Interim analyses will be preformed along the trial using the group sequential method. The analyses will be performed when sample size reaches 179, 357, 535, 713, and 891, respectively. Population: women with a pre-gestational BMI ≥ 30 undergoing planned or emergency caesarean section. The iNPWT or standard dressings is applied immediately following operation. In the intervention group the therapy will be left in situ for five days. In the control group the dressing will be left in situ for at least 24 hours as standard procedure. Follow-up is 30 days.Results: The study is on going. The first 179 participants are about to be analysed. Overall we expect to find a 50{\%} reduction of wound infection when using iNPWT compared to standard postoperative dressings in this high-risk subpopulation.",
keywords = "Negative Pressure Wound Therapy, Randomised Control Trials, Obesity, Caesarean Section, Negative Pressure Wound Therapy, Obesity, Randomised Control Trials, Caesarean Section",
author = "Nana Hyldig and Vinter, {Christina Anne} and Camilla Bille and Marie Kruse and Lamont, {Ronald Francis} and S{\o}rensen, {Jens Ahm} and Ole Mogensen and {Nyh{\o}j Heidemann}, Lene and {Holm Ibsen}, Mette and {Brink Laursen}, Jacob and Ovesen, {Per Glud} and Mette Tanvig and J{\o}rgensen, {Jan Stener}",
year = "2015",
month = "8",
day = "27",
language = "English",
note = "NOrdic Congress on Obesity in Gynaecology and Obestetrics , NOCOGO 2015 ; Conference date: 27-08-2015 Through 29-08-2015",

}

Incisional Negative Pressure Wound Therapy : Metod to reduce the risk of wound infection in obese women following caesarean section. / Hyldig, Nana; Vinter, Christina Anne; Bille, Camilla ; Kruse, Marie; Lamont, Ronald Francis; Sørensen, Jens Ahm; Mogensen, Ole; Nyhøj Heidemann, Lene; Holm Ibsen, Mette; Brink Laursen, Jacob; Ovesen, Per Glud; Tanvig, Mette; Jørgensen, Jan Stener.

2015. Poster session præsenteret på 2nd Nordic Congress on Obesity in Gynaecology and Obstetrics, Middelfart, Danmark.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

TY - CONF

T1 - Incisional Negative Pressure Wound Therapy

T2 - Metod to reduce the risk of wound infection in obese women following caesarean section

AU - Hyldig, Nana

AU - Vinter, Christina Anne

AU - Bille, Camilla

AU - Kruse, Marie

AU - Lamont, Ronald Francis

AU - Sørensen, Jens Ahm

AU - Mogensen, Ole

AU - Nyhøj Heidemann, Lene

AU - Holm Ibsen, Mette

AU - Brink Laursen, Jacob

AU - Ovesen, Per Glud

AU - Tanvig, Mette

AU - Jørgensen, Jan Stener

PY - 2015/8/27

Y1 - 2015/8/27

N2 - Background: Obese women undergoing caesarean section are at increased risk of surgical wound complications, which may lead to delayed recovery, pain, reduced quality of life, and increased health care cost. The aim of this study is to evaluate the effect of incisional Negative Pressure Wound Therapy (iNPWT) applied prophylactically following caesarean section compared with standard postoperative dressings in obese women undergoing caesarean section.Method: This study is designed as an unblinded, pragmatic, parallel randomised multicenter trial, with a 1:1 allocation. A computer random number generator are used to allocate the participants into one of two groups (iNPWT vs. standard dressing), stratified by centre and type of CS. The study is conducted at five public hospitals located in three regions of Denmark. Interim analyses will be preformed along the trial using the group sequential method. The analyses will be performed when sample size reaches 179, 357, 535, 713, and 891, respectively. Population: women with a pre-gestational BMI ≥ 30 undergoing planned or emergency caesarean section. The iNPWT or standard dressings is applied immediately following operation. In the intervention group the therapy will be left in situ for five days. In the control group the dressing will be left in situ for at least 24 hours as standard procedure. Follow-up is 30 days.Results: The study is on going. The first 179 participants are about to be analysed. Overall we expect to find a 50% reduction of wound infection when using iNPWT compared to standard postoperative dressings in this high-risk subpopulation.

AB - Background: Obese women undergoing caesarean section are at increased risk of surgical wound complications, which may lead to delayed recovery, pain, reduced quality of life, and increased health care cost. The aim of this study is to evaluate the effect of incisional Negative Pressure Wound Therapy (iNPWT) applied prophylactically following caesarean section compared with standard postoperative dressings in obese women undergoing caesarean section.Method: This study is designed as an unblinded, pragmatic, parallel randomised multicenter trial, with a 1:1 allocation. A computer random number generator are used to allocate the participants into one of two groups (iNPWT vs. standard dressing), stratified by centre and type of CS. The study is conducted at five public hospitals located in three regions of Denmark. Interim analyses will be preformed along the trial using the group sequential method. The analyses will be performed when sample size reaches 179, 357, 535, 713, and 891, respectively. Population: women with a pre-gestational BMI ≥ 30 undergoing planned or emergency caesarean section. The iNPWT or standard dressings is applied immediately following operation. In the intervention group the therapy will be left in situ for five days. In the control group the dressing will be left in situ for at least 24 hours as standard procedure. Follow-up is 30 days.Results: The study is on going. The first 179 participants are about to be analysed. Overall we expect to find a 50% reduction of wound infection when using iNPWT compared to standard postoperative dressings in this high-risk subpopulation.

KW - Negative Pressure Wound Therapy

KW - Randomised Control Trials

KW - Obesity

KW - Caesarean Section

KW - Negative Pressure Wound Therapy

KW - Obesity

KW - Randomised Control Trials

KW - Caesarean Section

M3 - Poster

ER -

Hyldig N, Vinter CA, Bille C, Kruse M, Lamont RF, Sørensen JA et al. Incisional Negative Pressure Wound Therapy: Metod to reduce the risk of wound infection in obese women following caesarean section. 2015. Poster session præsenteret på 2nd Nordic Congress on Obesity in Gynaecology and Obstetrics, Middelfart, Danmark.