Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors

Rachel M Shaffer, Samuel P Sellers, Marissa G Baker, Rebeca de Buen Kalman, Joseph Frostad, Megan K Suter, Susan C Anenberg, John Balbus, Niladri Basu, David C Bellinger, Linda Birnbaum, Michael Brauer, Aaron Cohen, Kristie L Ebi, Richard Fuller, Philippe Grandjean, Jeremy J Hess, Manolis Kogevinas, Pushpam Kumar, Philip J LandriganBruce Lanphear, Stephanie J London, Andrew A Rooney, Jeffrey D Stanaway, Leonardo Trasande, Katherine Walker, Howard Hu

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Resumé

BACKGROUND: The Global Burden of Disease (GBD) study, coordinated by the Institute for Health Metrics and Evaluation (IHME), produces influential, data-driven estimates of the burden of disease and premature death due to major risk factors. Expanded quantification of disease due to environmental health (EH) risk factors, including climate change, will enhance accuracy of GBD estimates, which will contribute to developing cost-effective policies that promote prevention and achieving Sustainable Development Goals.

OBJECTIVES: We review key aspects of the GBD for the EH community and introduce the Global Burden of Disease-Pollution and Health Initiative (GBD-PHI), which aims to work with IHME and the GBD study to improve estimates of disease burden attributable to EH risk factors and to develop an innovative approach to estimating climate-related disease burden-both current and projected.

METHODS: We discuss strategies for improving GBD quantification of specific EH risk factors, including air pollution, lead, and climate change. We highlight key methodological challenges, including new EH risk factors, notably evidence rating and global exposure assessment.

DISCUSSION: A number of issues present challenges to the scope and accuracy of current GBD estimates for EH risk factors. For air pollution, minimal data exist on the exposure-risk relationships associated with high levels of pollution; epidemiological studies in high pollution regions should be a research priority. For lead, the GBD's current methods do not fully account for lead's impact on neurodevelopment; innovative methods to account for subclinical effects are needed. Decisions on inclusion of additional EH risk-outcome pairs need to be guided by findings of systematic reviews, the size of exposed populations, feasibility of global exposure estimates, and predicted trends in exposures and diseases. Neurotoxicants, endocrine-disrupting chemicals, and climate-related factors should be high priorities for incorporation into upcoming iterations of the GBD study. Enhancing the scope and methods will improve the GBD's estimates and better guide prevention policy. https://doi.org/10.1289/EHP5496.

OriginalsprogEngelsk
TidsskriftEnvironmental Health Perspectives
Vol/bind127
Udgave nummer10
Sider (fra-til)105001-1-105001-16
ISSN0091-6765
DOI
StatusUdgivet - okt. 2019

Fingeraftryk

Environmental Health
Air Pollution
Health
Endocrine Disruptors
Premature Mortality
Global Burden of Disease
Population Density
Epidemiologic Studies
Research

Citer dette

Shaffer, R. M., Sellers, S. P., Baker, M. G., de Buen Kalman, R., Frostad, J., Suter, M. K., ... Hu, H. (2019). Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors. Environmental Health Perspectives, 127(10), 105001-1-105001-16. https://doi.org/10.1289/EHP5496
Shaffer, Rachel M ; Sellers, Samuel P ; Baker, Marissa G ; de Buen Kalman, Rebeca ; Frostad, Joseph ; Suter, Megan K ; Anenberg, Susan C ; Balbus, John ; Basu, Niladri ; Bellinger, David C ; Birnbaum, Linda ; Brauer, Michael ; Cohen, Aaron ; Ebi, Kristie L ; Fuller, Richard ; Grandjean, Philippe ; Hess, Jeremy J ; Kogevinas, Manolis ; Kumar, Pushpam ; Landrigan, Philip J ; Lanphear, Bruce ; London, Stephanie J ; Rooney, Andrew A ; Stanaway, Jeffrey D ; Trasande, Leonardo ; Walker, Katherine ; Hu, Howard. / Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors. I: Environmental Health Perspectives. 2019 ; Bind 127, Nr. 10. s. 105001-1-105001-16.
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abstract = "BACKGROUND: The Global Burden of Disease (GBD) study, coordinated by the Institute for Health Metrics and Evaluation (IHME), produces influential, data-driven estimates of the burden of disease and premature death due to major risk factors. Expanded quantification of disease due to environmental health (EH) risk factors, including climate change, will enhance accuracy of GBD estimates, which will contribute to developing cost-effective policies that promote prevention and achieving Sustainable Development Goals.OBJECTIVES: We review key aspects of the GBD for the EH community and introduce the Global Burden of Disease-Pollution and Health Initiative (GBD-PHI), which aims to work with IHME and the GBD study to improve estimates of disease burden attributable to EH risk factors and to develop an innovative approach to estimating climate-related disease burden-both current and projected.METHODS: We discuss strategies for improving GBD quantification of specific EH risk factors, including air pollution, lead, and climate change. We highlight key methodological challenges, including new EH risk factors, notably evidence rating and global exposure assessment.DISCUSSION: A number of issues present challenges to the scope and accuracy of current GBD estimates for EH risk factors. For air pollution, minimal data exist on the exposure-risk relationships associated with high levels of pollution; epidemiological studies in high pollution regions should be a research priority. For lead, the GBD's current methods do not fully account for lead's impact on neurodevelopment; innovative methods to account for subclinical effects are needed. Decisions on inclusion of additional EH risk-outcome pairs need to be guided by findings of systematic reviews, the size of exposed populations, feasibility of global exposure estimates, and predicted trends in exposures and diseases. Neurotoxicants, endocrine-disrupting chemicals, and climate-related factors should be high priorities for incorporation into upcoming iterations of the GBD study. Enhancing the scope and methods will improve the GBD's estimates and better guide prevention policy. https://doi.org/10.1289/EHP5496.",
author = "Shaffer, {Rachel M} and Sellers, {Samuel P} and Baker, {Marissa G} and {de Buen Kalman}, Rebeca and Joseph Frostad and Suter, {Megan K} and Anenberg, {Susan C} and John Balbus and Niladri Basu and Bellinger, {David C} and Linda Birnbaum and Michael Brauer and Aaron Cohen and Ebi, {Kristie L} and Richard Fuller and Philippe Grandjean and Hess, {Jeremy J} and Manolis Kogevinas and Pushpam Kumar and Landrigan, {Philip J} and Bruce Lanphear and London, {Stephanie J} and Rooney, {Andrew A} and Stanaway, {Jeffrey D} and Leonardo Trasande and Katherine Walker and Howard Hu",
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Shaffer, RM, Sellers, SP, Baker, MG, de Buen Kalman, R, Frostad, J, Suter, MK, Anenberg, SC, Balbus, J, Basu, N, Bellinger, DC, Birnbaum, L, Brauer, M, Cohen, A, Ebi, KL, Fuller, R, Grandjean, P, Hess, JJ, Kogevinas, M, Kumar, P, Landrigan, PJ, Lanphear, B, London, SJ, Rooney, AA, Stanaway, JD, Trasande, L, Walker, K & Hu, H 2019, 'Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors', Environmental Health Perspectives, bind 127, nr. 10, s. 105001-1-105001-16. https://doi.org/10.1289/EHP5496

Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors. / Shaffer, Rachel M; Sellers, Samuel P; Baker, Marissa G; de Buen Kalman, Rebeca; Frostad, Joseph; Suter, Megan K; Anenberg, Susan C; Balbus, John; Basu, Niladri; Bellinger, David C; Birnbaum, Linda; Brauer, Michael; Cohen, Aaron; Ebi, Kristie L; Fuller, Richard; Grandjean, Philippe; Hess, Jeremy J; Kogevinas, Manolis; Kumar, Pushpam; Landrigan, Philip J; Lanphear, Bruce; London, Stephanie J; Rooney, Andrew A; Stanaway, Jeffrey D; Trasande, Leonardo; Walker, Katherine; Hu, Howard.

I: Environmental Health Perspectives, Bind 127, Nr. 10, 10.2019, s. 105001-1-105001-16.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors

AU - Shaffer, Rachel M

AU - Sellers, Samuel P

AU - Baker, Marissa G

AU - de Buen Kalman, Rebeca

AU - Frostad, Joseph

AU - Suter, Megan K

AU - Anenberg, Susan C

AU - Balbus, John

AU - Basu, Niladri

AU - Bellinger, David C

AU - Birnbaum, Linda

AU - Brauer, Michael

AU - Cohen, Aaron

AU - Ebi, Kristie L

AU - Fuller, Richard

AU - Grandjean, Philippe

AU - Hess, Jeremy J

AU - Kogevinas, Manolis

AU - Kumar, Pushpam

AU - Landrigan, Philip J

AU - Lanphear, Bruce

AU - London, Stephanie J

AU - Rooney, Andrew A

AU - Stanaway, Jeffrey D

AU - Trasande, Leonardo

AU - Walker, Katherine

AU - Hu, Howard

PY - 2019/10

Y1 - 2019/10

N2 - BACKGROUND: The Global Burden of Disease (GBD) study, coordinated by the Institute for Health Metrics and Evaluation (IHME), produces influential, data-driven estimates of the burden of disease and premature death due to major risk factors. Expanded quantification of disease due to environmental health (EH) risk factors, including climate change, will enhance accuracy of GBD estimates, which will contribute to developing cost-effective policies that promote prevention and achieving Sustainable Development Goals.OBJECTIVES: We review key aspects of the GBD for the EH community and introduce the Global Burden of Disease-Pollution and Health Initiative (GBD-PHI), which aims to work with IHME and the GBD study to improve estimates of disease burden attributable to EH risk factors and to develop an innovative approach to estimating climate-related disease burden-both current and projected.METHODS: We discuss strategies for improving GBD quantification of specific EH risk factors, including air pollution, lead, and climate change. We highlight key methodological challenges, including new EH risk factors, notably evidence rating and global exposure assessment.DISCUSSION: A number of issues present challenges to the scope and accuracy of current GBD estimates for EH risk factors. For air pollution, minimal data exist on the exposure-risk relationships associated with high levels of pollution; epidemiological studies in high pollution regions should be a research priority. For lead, the GBD's current methods do not fully account for lead's impact on neurodevelopment; innovative methods to account for subclinical effects are needed. Decisions on inclusion of additional EH risk-outcome pairs need to be guided by findings of systematic reviews, the size of exposed populations, feasibility of global exposure estimates, and predicted trends in exposures and diseases. Neurotoxicants, endocrine-disrupting chemicals, and climate-related factors should be high priorities for incorporation into upcoming iterations of the GBD study. Enhancing the scope and methods will improve the GBD's estimates and better guide prevention policy. https://doi.org/10.1289/EHP5496.

AB - BACKGROUND: The Global Burden of Disease (GBD) study, coordinated by the Institute for Health Metrics and Evaluation (IHME), produces influential, data-driven estimates of the burden of disease and premature death due to major risk factors. Expanded quantification of disease due to environmental health (EH) risk factors, including climate change, will enhance accuracy of GBD estimates, which will contribute to developing cost-effective policies that promote prevention and achieving Sustainable Development Goals.OBJECTIVES: We review key aspects of the GBD for the EH community and introduce the Global Burden of Disease-Pollution and Health Initiative (GBD-PHI), which aims to work with IHME and the GBD study to improve estimates of disease burden attributable to EH risk factors and to develop an innovative approach to estimating climate-related disease burden-both current and projected.METHODS: We discuss strategies for improving GBD quantification of specific EH risk factors, including air pollution, lead, and climate change. We highlight key methodological challenges, including new EH risk factors, notably evidence rating and global exposure assessment.DISCUSSION: A number of issues present challenges to the scope and accuracy of current GBD estimates for EH risk factors. For air pollution, minimal data exist on the exposure-risk relationships associated with high levels of pollution; epidemiological studies in high pollution regions should be a research priority. For lead, the GBD's current methods do not fully account for lead's impact on neurodevelopment; innovative methods to account for subclinical effects are needed. Decisions on inclusion of additional EH risk-outcome pairs need to be guided by findings of systematic reviews, the size of exposed populations, feasibility of global exposure estimates, and predicted trends in exposures and diseases. Neurotoxicants, endocrine-disrupting chemicals, and climate-related factors should be high priorities for incorporation into upcoming iterations of the GBD study. Enhancing the scope and methods will improve the GBD's estimates and better guide prevention policy. https://doi.org/10.1289/EHP5496.

U2 - 10.1289/EHP5496

DO - 10.1289/EHP5496

M3 - Journal article

C2 - 31626566

VL - 127

SP - 105001-1-105001-16

JO - Environmental Health Perspectives

JF - Environmental Health Perspectives

SN - 0091-6765

IS - 10

ER -

Shaffer RM, Sellers SP, Baker MG, de Buen Kalman R, Frostad J, Suter MK et al. Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors. Environmental Health Perspectives. 2019 okt;127(10):105001-1-105001-16. https://doi.org/10.1289/EHP5496