Improved overall survival after late recurrence of lung cancer following the introduction of CT-based follow-up for patients treated with curative intent

Background: After introduction in July 2010 of follow-up by contrast enhanced CT of thorax and upper abdomen every 3 months for two years and then every 6 months for three years we have found improved survival after early recurrence in patients initially treated with curative intent by surgery as well as by chemoradiotherapy (Eur Respir J 2017; 50 suppl 61: PA4271).Aim: To study overall survival of patients having late recurrence (after 24 but within 60 months) after the end of initial therapy.Methods: Every patient from Funen county treated with curative intent from January 2005 to June 2014 and alive without recurrence after 24 months was included (n=503). Vital status and recurrence status were updated from the Danish Lung Cancer Registry in January 2018.Results: In total 110 patients have had a late recurrence. The table shows the estimated survival (95 from the end of initial therapy comparing the groups diagnosed during the 5textonehalf years before and the 4 years after the introduction of the CT-based follow-up (plt;0.001, log rank test, HR = 0.35, 95 0.20-0.60). The fraction of the patients having a second treatment with curative intent has increased from 21.2% before to 63.6% after the introduction of CT-based follow-up: OR = 6.5 (95 2.8-15.2).Conclusion: The CT-based follow-up program has most likely improved survival by increasing the fraction of patients having a second treatment with curative intent. View this table:FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA1770.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).