Improved overall survival after late recurrence of lung cancer following the introduction of CT-based follow-up for patients treated with curative intent

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Resumé

Background: After introduction in July 2010 of follow-up by contrast enhanced CT of thorax and upper abdomen every 3 months for two years and then every 6 months for three years we have found improved survival after early recurrence in patients initially treated with curative intent by surgery as well as by chemoradiotherapy (Eur Respir J 2017; 50 suppl 61: PA4271).Aim: To study overall survival of patients having late recurrence (after 24 but within 60 months) after the end of initial therapy.Methods: Every patient from Funen county treated with curative intent from January 2005 to June 2014 and alive without recurrence after 24 months was included (n=503). Vital status and recurrence status were updated from the Danish Lung Cancer Registry in January 2018.Results: In total 110 patients have had a late recurrence. The table shows the estimated survival (95 from the end of initial therapy comparing the groups diagnosed during the 5textonehalf years before and the 4 years after the introduction of the CT-based follow-up (plt;0.001, log rank test, HR = 0.35, 95 0.20-0.60). The fraction of the patients having a second treatment with curative intent has increased from 21.2% before to 63.6% after the introduction of CT-based follow-up: OR = 6.5 (95 2.8-15.2).Conclusion: The CT-based follow-up program has most likely improved survival by increasing the fraction of patients having a second treatment with curative intent. View this table:FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA1770.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
OriginalsprogEngelsk
ArtikelnummerPA1770
TidsskriftEuropean Respiratory Journal
Vol/bind52
Udgave nummerSuppl. 62
Antal sider1
ISSN0903-1936
DOI
StatusUdgivet - 2018
BegivenhedERS International Congress 2018 - Paris, Frankrig
Varighed: 15. sep. 201819. sep. 2018

Konference

KonferenceERS International Congress 2018
LandFrankrig
ByParis
Periode15/09/201819/09/2018

Fingeraftryk

Registries
Education

Citer dette

@article{b7de37a3b4474483add65d65da8e7048,
title = "Improved overall survival after late recurrence of lung cancer following the introduction of CT-based follow-up for patients treated with curative intent",
abstract = "Background: After introduction in July 2010 of follow-up by contrast enhanced CT of thorax and upper abdomen every 3 months for two years and then every 6 months for three years we have found improved survival after early recurrence in patients initially treated with curative intent by surgery as well as by chemoradiotherapy (Eur Respir J 2017; 50 suppl 61: PA4271).Aim: To study overall survival of patients having late recurrence (after 24 but within 60 months) after the end of initial therapy.Methods: Every patient from Funen county treated with curative intent from January 2005 to June 2014 and alive without recurrence after 24 months was included (n=503). Vital status and recurrence status were updated from the Danish Lung Cancer Registry in January 2018.Results: In total 110 patients have had a late recurrence. The table shows the estimated survival (95 from the end of initial therapy comparing the groups diagnosed during the 5textonehalf years before and the 4 years after the introduction of the CT-based follow-up (plt;0.001, log rank test, HR = 0.35, 95 0.20-0.60). The fraction of the patients having a second treatment with curative intent has increased from 21.2{\%} before to 63.6{\%} after the introduction of CT-based follow-up: OR = 6.5 (95 2.8-15.2).Conclusion: The CT-based follow-up program has most likely improved survival by increasing the fraction of patients having a second treatment with curative intent. View this table:FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA1770.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).",
author = "Hansen, {Niels-Chr. G.} and Jeppesen, {Stefan S.} and Laursen, {Christian B.} and Erik Jakobsen",
year = "2018",
doi = "10.1183/13993003.congress-2018.PA1770",
language = "English",
volume = "52",
journal = "European Respiratory Journal",
issn = "0903-1936",
publisher = "European Respiratory Society",
number = "Suppl. 62",

}

TY - ABST

T1 - Improved overall survival after late recurrence of lung cancer following the introduction of CT-based follow-up for patients treated with curative intent

AU - Hansen, Niels-Chr. G.

AU - Jeppesen, Stefan S.

AU - Laursen, Christian B.

AU - Jakobsen, Erik

PY - 2018

Y1 - 2018

N2 - Background: After introduction in July 2010 of follow-up by contrast enhanced CT of thorax and upper abdomen every 3 months for two years and then every 6 months for three years we have found improved survival after early recurrence in patients initially treated with curative intent by surgery as well as by chemoradiotherapy (Eur Respir J 2017; 50 suppl 61: PA4271).Aim: To study overall survival of patients having late recurrence (after 24 but within 60 months) after the end of initial therapy.Methods: Every patient from Funen county treated with curative intent from January 2005 to June 2014 and alive without recurrence after 24 months was included (n=503). Vital status and recurrence status were updated from the Danish Lung Cancer Registry in January 2018.Results: In total 110 patients have had a late recurrence. The table shows the estimated survival (95 from the end of initial therapy comparing the groups diagnosed during the 5textonehalf years before and the 4 years after the introduction of the CT-based follow-up (plt;0.001, log rank test, HR = 0.35, 95 0.20-0.60). The fraction of the patients having a second treatment with curative intent has increased from 21.2% before to 63.6% after the introduction of CT-based follow-up: OR = 6.5 (95 2.8-15.2).Conclusion: The CT-based follow-up program has most likely improved survival by increasing the fraction of patients having a second treatment with curative intent. View this table:FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA1770.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

AB - Background: After introduction in July 2010 of follow-up by contrast enhanced CT of thorax and upper abdomen every 3 months for two years and then every 6 months for three years we have found improved survival after early recurrence in patients initially treated with curative intent by surgery as well as by chemoradiotherapy (Eur Respir J 2017; 50 suppl 61: PA4271).Aim: To study overall survival of patients having late recurrence (after 24 but within 60 months) after the end of initial therapy.Methods: Every patient from Funen county treated with curative intent from January 2005 to June 2014 and alive without recurrence after 24 months was included (n=503). Vital status and recurrence status were updated from the Danish Lung Cancer Registry in January 2018.Results: In total 110 patients have had a late recurrence. The table shows the estimated survival (95 from the end of initial therapy comparing the groups diagnosed during the 5textonehalf years before and the 4 years after the introduction of the CT-based follow-up (plt;0.001, log rank test, HR = 0.35, 95 0.20-0.60). The fraction of the patients having a second treatment with curative intent has increased from 21.2% before to 63.6% after the introduction of CT-based follow-up: OR = 6.5 (95 2.8-15.2).Conclusion: The CT-based follow-up program has most likely improved survival by increasing the fraction of patients having a second treatment with curative intent. View this table:FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA1770.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

U2 - 10.1183/13993003.congress-2018.PA1770

DO - 10.1183/13993003.congress-2018.PA1770

M3 - Conference abstract in journal

VL - 52

JO - European Respiratory Journal

JF - European Respiratory Journal

SN - 0903-1936

IS - Suppl. 62

M1 - PA1770

ER -