Hybrid CT angiography and quantitative (15)O-water PET for assessment of coronary artery disease: comparison with quantitative coronary angiography

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

CT angiography (CTA) can rule out significant stenoses with a very high reliability, whereas its ability to confirm significant stenoses is suboptimal. In contrast, measurements of myocardial blood flow (MBF) provide information on the haemodynamic consequences of stenoses. Therefore, a combination of the two might improve diagnostic accuracy. We conducted a head-to-head comparison of CTA, measurement of MBF by (15)O-water PET, and hybrid PET/CTA for the detection of significant coronary artery stenoses.
OriginalsprogEngelsk
TidsskriftEuropean Journal of Nuclear Medicine and Molecular Imaging
Vol/bind40
Udgave nummer12
Sider (fra-til)1894-1904
ISSN1619-7070
DOI
StatusUdgivet - 2013

Fingeraftryk

Coronary Angiography
Coronary Artery Disease
Pathologic Constriction
Computed Tomography Angiography

Citer dette

@article{e19beb51ae7241839b613266286434f5,
title = "Hybrid CT angiography and quantitative (15)O-water PET for assessment of coronary artery disease: comparison with quantitative coronary angiography",
abstract = "CT angiography (CTA) can rule out significant stenoses with a very high reliability, whereas its ability to confirm significant stenoses is suboptimal. In contrast, measurements of myocardial blood flow (MBF) provide information on the haemodynamic consequences of stenoses. Therefore, a combination of the two might improve diagnostic accuracy. We conducted a head-to-head comparison of CTA, measurement of MBF by (15)O-water PET, and hybrid PET/CTA for the detection of significant coronary artery stenoses.",
author = "Anders Thomassen and Henrik Petersen and Diederichsen, {Axel C P} and Hans Mickley and Jensen, {Lisette O} and Allan Johansen and Oke Gerke and Poul-Erik Braad and Per Thayssen and H{\o}ilund-Carlsen, {Mette M} and Werner Vach and Juhani Knuuti and H{\o}ilund-Carlsen, {Poul F}",
year = "2013",
doi = "10.1007/s00259-013-2519-3",
language = "English",
volume = "40",
pages = "1894--1904",
journal = "European Journal of Nuclear Medicine and Molecular Imaging",
issn = "1619-7070",
publisher = "Heinemann",
number = "12",

}

TY - JOUR

T1 - Hybrid CT angiography and quantitative (15)O-water PET for assessment of coronary artery disease

T2 - comparison with quantitative coronary angiography

AU - Thomassen, Anders

AU - Petersen, Henrik

AU - Diederichsen, Axel C P

AU - Mickley, Hans

AU - Jensen, Lisette O

AU - Johansen, Allan

AU - Gerke, Oke

AU - Braad, Poul-Erik

AU - Thayssen, Per

AU - Høilund-Carlsen, Mette M

AU - Vach, Werner

AU - Knuuti, Juhani

AU - Høilund-Carlsen, Poul F

PY - 2013

Y1 - 2013

N2 - CT angiography (CTA) can rule out significant stenoses with a very high reliability, whereas its ability to confirm significant stenoses is suboptimal. In contrast, measurements of myocardial blood flow (MBF) provide information on the haemodynamic consequences of stenoses. Therefore, a combination of the two might improve diagnostic accuracy. We conducted a head-to-head comparison of CTA, measurement of MBF by (15)O-water PET, and hybrid PET/CTA for the detection of significant coronary artery stenoses.

AB - CT angiography (CTA) can rule out significant stenoses with a very high reliability, whereas its ability to confirm significant stenoses is suboptimal. In contrast, measurements of myocardial blood flow (MBF) provide information on the haemodynamic consequences of stenoses. Therefore, a combination of the two might improve diagnostic accuracy. We conducted a head-to-head comparison of CTA, measurement of MBF by (15)O-water PET, and hybrid PET/CTA for the detection of significant coronary artery stenoses.

U2 - 10.1007/s00259-013-2519-3

DO - 10.1007/s00259-013-2519-3

M3 - Journal article

C2 - 23982453

VL - 40

SP - 1894

EP - 1904

JO - European Journal of Nuclear Medicine and Molecular Imaging

JF - European Journal of Nuclear Medicine and Molecular Imaging

SN - 1619-7070

IS - 12

ER -