Highly fluorescent benzofuran derivatives of the GFP chromophore

M. A. Christensen; Karsten Stein Jennum; P. B. Abrahamsen; E. A. Della Pia; K. Lincke; Søren Lindbæk Broman; D. B. Nygaard; A. D. Bond; M. B. Nielsen

doi:10.1039/c2ra21380j

Highly fluorescent benzofuran derivatives of the GFP chromophore

M. A. Christensen
, Karsten Stein Jennum
, P. B. Abrahamsen
, E. A. Della Pia
, K. Lincke
, Søren Lindbæk Broman
, D. B. Nygaard
, A. D. Bond
, M. B. Nielsen

Institut for Fysik, Kemi og Farmaci

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

Intramolecular cyclization reactions of Green Fluorescent Protein chromophores (GFPc) containing an arylethynyl ortho-substituent at the phenol ring provide new aryl-substituted benzofuran derivatives of the GFPc. Some of these heteroaromatic compounds exhibit significantly enhanced fluorescence at red-shifted emission wavelengths relative to the parent GFPc structure.

Originalsprog	Engelsk
Tidsskrift	R S C Advances
Vol/bind	2
Udgave nummer	22
Sider (fra-til)	8243-8249
Antal sider	7
ISSN	2046-2069
DOI	https://doi.org/10.1039/c2ra21380j
Status	Udgivet - 2012

Dokumenter og links

10.1039/c2ra21380j

SDU link

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Citationsformater

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title = "Highly fluorescent benzofuran derivatives of the GFP chromophore",

abstract = "Intramolecular cyclization reactions of Green Fluorescent Protein chromophores (GFPc) containing an arylethynyl ortho-substituent at the phenol ring provide new aryl-substituted benzofuran derivatives of the GFPc. Some of these heteroaromatic compounds exhibit significantly enhanced fluorescence at red-shifted emission wavelengths relative to the parent GFPc structure.",

author = "Christensen, \{M. A.\} and Jennum, \{Karsten Stein\} and Abrahamsen, \{P. B.\} and \{Della Pia\}, \{E. A.\} and K. Lincke and Broman, \{S{\o}ren Lindb{\ae}k\} and Nygaard, \{D. B.\} and Bond, \{A. D.\} and Nielsen, \{M. B.\}",

year = "2012",

doi = "10.1039/c2ra21380j",

language = "English",

volume = "2",

pages = "8243--8249",

journal = "R S C Advances",

issn = "2046-2069",

publisher = "Royal Society of Chemistry",

number = "22",

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TY - JOUR

T1 - Highly fluorescent benzofuran derivatives of the GFP chromophore

AU - Christensen, M. A.

AU - Jennum, Karsten Stein

AU - Abrahamsen, P. B.

AU - Della Pia, E. A.

AU - Lincke, K.

AU - Broman, Søren Lindbæk

AU - Nygaard, D. B.

AU - Bond, A. D.

AU - Nielsen, M. B.

PY - 2012

Y1 - 2012

N2 - Intramolecular cyclization reactions of Green Fluorescent Protein chromophores (GFPc) containing an arylethynyl ortho-substituent at the phenol ring provide new aryl-substituted benzofuran derivatives of the GFPc. Some of these heteroaromatic compounds exhibit significantly enhanced fluorescence at red-shifted emission wavelengths relative to the parent GFPc structure.

AB - Intramolecular cyclization reactions of Green Fluorescent Protein chromophores (GFPc) containing an arylethynyl ortho-substituent at the phenol ring provide new aryl-substituted benzofuran derivatives of the GFPc. Some of these heteroaromatic compounds exhibit significantly enhanced fluorescence at red-shifted emission wavelengths relative to the parent GFPc structure.

U2 - 10.1039/c2ra21380j

DO - 10.1039/c2ra21380j

M3 - Journal article

SN - 2046-2069

VL - 2

SP - 8243

EP - 8249

JO - R S C Advances

JF - R S C Advances

IS - 22

ER -