Helicobacter pylori

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Helicobacter pylori (HP) are Gram-negative spiral bacteria which occur in the human stomach. The bacteria were cultured in vitro for the first time in 1983. It is suspected that the bacteria may cause chronic gastritis of type B and may also be a contributory cause of chronic ulceration and cancer of the stomach. The bacteria are accompanied by characteristic inflammatory changes in the gastric mucosa. The significance for gastritis, chronic ulceration, non-ulcer dyspepsia and carcinoma of the stomach is discussed. HP occurs in a great proportion of the population of the world and the frequency increases with age. The route of infection is unknown but faecal-oral infection is probable. Correlation between the presence of HP and the occurrence of symptoms is poor in the individual patient. The bacteria can be demonstrated histologically, cytologically, by culture, by the urease test, by the urease expiration test or serologically. The bacteria are sensitive for a series of antibiotics and bismuth but no effective treatment is known as the recurrence rate is high.
OriginalsprogDansk
TidsskriftUgeskrift for læger
Vol/bind154
Udgave nummer24
Sider (fra-til)1682-1686
ISSN0041-5782
StatusUdgivet - 1992

Emneord

  • Infection

Citer dette

Leth, Peter Mygind. / Helicobacter pylori. I: Ugeskrift for læger. 1992 ; Bind 154, Nr. 24. s. 1682-1686.
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Leth, PM 1992, 'Helicobacter pylori', Ugeskrift for læger, bind 154, nr. 24, s. 1682-1686.

Helicobacter pylori. / Leth, Peter Mygind.

I: Ugeskrift for læger, Bind 154, Nr. 24, 1992, s. 1682-1686.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Helicobacter pylori

AU - Leth, Peter Mygind

PY - 1992

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N2 - Helicobacter pylori (HP) are Gram-negative spiral bacteria which occur in the human stomach. The bacteria were cultured in vitro for the first time in 1983. It is suspected that the bacteria may cause chronic gastritis of type B and may also be a contributory cause of chronic ulceration and cancer of the stomach. The bacteria are accompanied by characteristic inflammatory changes in the gastric mucosa. The significance for gastritis, chronic ulceration, non-ulcer dyspepsia and carcinoma of the stomach is discussed. HP occurs in a great proportion of the population of the world and the frequency increases with age. The route of infection is unknown but faecal-oral infection is probable. Correlation between the presence of HP and the occurrence of symptoms is poor in the individual patient. The bacteria can be demonstrated histologically, cytologically, by culture, by the urease test, by the urease expiration test or serologically. The bacteria are sensitive for a series of antibiotics and bismuth but no effective treatment is known as the recurrence rate is high.

AB - Helicobacter pylori (HP) are Gram-negative spiral bacteria which occur in the human stomach. The bacteria were cultured in vitro for the first time in 1983. It is suspected that the bacteria may cause chronic gastritis of type B and may also be a contributory cause of chronic ulceration and cancer of the stomach. The bacteria are accompanied by characteristic inflammatory changes in the gastric mucosa. The significance for gastritis, chronic ulceration, non-ulcer dyspepsia and carcinoma of the stomach is discussed. HP occurs in a great proportion of the population of the world and the frequency increases with age. The route of infection is unknown but faecal-oral infection is probable. Correlation between the presence of HP and the occurrence of symptoms is poor in the individual patient. The bacteria can be demonstrated histologically, cytologically, by culture, by the urease test, by the urease expiration test or serologically. The bacteria are sensitive for a series of antibiotics and bismuth but no effective treatment is known as the recurrence rate is high.

KW - Infection

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VL - 154

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EP - 1686

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SN - 0041-5782

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