Health related quality of life in a nationally representative sample of haematological patients

Anna T Johnsen, Dorte Tholstrup, Morten Aa Petersen, Lise Pedersen, Mogens Groenvold

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

OBJECTIVES: Knowledge of health related quality of life of haematological patients is limited. This study aimed at investigating the prevalence and predictors of symptoms and problems in a representative sample of haematological patients in Denmark.

METHODS: A random sample of patients with leukaemia, multiple myeloma and advanced lymphoma (n = 732) received the European Organisation for Research and Treatment of Cancer quality-of-life questionnaire (EORTC QLQ-C30). Mean scores were calculated. In addition, scores were dichotomised using two thresholds: patients reporting at least 'a little' of each EORTC QLQ-C30 symptom/problem were classified as having a 'symptom/problem', and patients reporting at least 'quite a bit' were classified as having a 'severe symptom/problem'. Multiple logistic regression was used to identify predictors.

RESULTS: In total, 470 (64%) patients participated. The most frequent symptoms/problems were fatigue (55%; severe 20%), reduced role function (49%; severe 23%), insomnia (46%; severe 15%), and pain (37%; severe 15%). Older patients and patients in active antineoplastic treatment had more symptoms and problems. There was only little evidence of social inequalities.

CONCLUSION: This is probably the first nationally representative study of symptoms and problems in haematological patients. These patients have symptoms/problems that deserve attention. Health related quality of life is an important issue in haematological malignancies.

OriginalsprogEngelsk
TidsskriftEuropean journal of haematology
Vol/bind83
Udgave nummer2
Sider (fra-til)139-48
Antal sider10
DOI
StatusUdgivet - aug. 2009
Udgivet eksterntJa

Emneord

  • Aged
  • Denmark
  • Female
  • Humans
  • Leukemia
  • Lymphoma
  • Male
  • Middle Aged
  • Multiple Myeloma
  • Neoplasm Staging
  • Quality of Life
  • Questionnaires
  • Risk Assessment

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