Health of children born to mothers who had preeclampsia: a population-based cohort study

Chunsen Wu, Ellen Aagaard Nøhr, Bodil H Bech, Mogens Vestergaard, Janet M Catov, Jørn Olsen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Udgivelsesdato: 2009-Sep
OriginalsprogEngelsk
TidsskriftAmerican Journal of Obstetrics and Gynecology
Vol/bind201
Udgave nummer3
Sider (fra-til)269.e1-269.e10
Antal sider10
ISSN0002-9378
DOI
StatusUdgivet - 2009
Udgivet eksterntJa

Fingeraftryk

Pre-Eclampsia
Cohort Studies
Mothers
Population
Confidence Intervals
Nutritional and Metabolic Diseases
Incidence
Endocrine System Diseases
Hematologic Diseases
Health
Cerebral Palsy
Denmark
Child Health

Bibliografisk note

Paper id:: doi:10.1016/j.ajog.2009.06.060

Citer dette

Wu, Chunsen ; Nøhr, Ellen Aagaard ; Bech, Bodil H ; Vestergaard, Mogens ; Catov, Janet M ; Olsen, Jørn. / Health of children born to mothers who had preeclampsia: a population-based cohort study. I: American Journal of Obstetrics and Gynecology. 2009 ; Bind 201, Nr. 3. s. 269.e1-269.e10.
@article{20da8f914ea644df93fd7dc83a091d20,
title = "Health of children born to mothers who had preeclampsia: a population-based cohort study",
abstract = "OBJECTIVE: We assessed whether preeclampsia correlates with the long-term postnatal health of the offspring. STUDY DESIGN: We conducted a population-based cohort study of 1,618,481 singletons born in Denmark (1978-2004) with up to 27 years of follow-up. We used Cox regression to estimate the associations between preeclampsia and long-term health outcomes of the offspring. RESULTS: Children born at term exposed to preeclampsia had an increased risk of a variety of diseases, such as endocrine, nutritional, and metabolic diseases (incidence rate ratio, 1.6; 95{\%} confidence interval, 1.5-1.7), and diseases of the blood and blood-forming organs (incidence rate ratio, 1.5; 95{\%} confidence interval, 1.3-1.8). Children born preterm exposed to preeclampsia had a similar pattern of hospitalizations compared with the children born preterm unexposed to preeclampsia, although they had a decreased risk of cerebral palsy (incidence rate ratio, 0.7; 95{\%} confidence interval, 0.6-0.9). CONCLUSION: Preeclampsia was associated with an increased risk of being hospitalized for a number of diseases, especially in the children born at term.",
author = "Chunsen Wu and N{\o}hr, {Ellen Aagaard} and Bech, {Bodil H} and Mogens Vestergaard and Catov, {Janet M} and J{\o}rn Olsen",
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Health of children born to mothers who had preeclampsia: a population-based cohort study. / Wu, Chunsen; Nøhr, Ellen Aagaard; Bech, Bodil H; Vestergaard, Mogens; Catov, Janet M; Olsen, Jørn.

I: American Journal of Obstetrics and Gynecology, Bind 201, Nr. 3, 2009, s. 269.e1-269.e10.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Health of children born to mothers who had preeclampsia: a population-based cohort study

AU - Wu, Chunsen

AU - Nøhr, Ellen Aagaard

AU - Bech, Bodil H

AU - Vestergaard, Mogens

AU - Catov, Janet M

AU - Olsen, Jørn

N1 - Paper id:: doi:10.1016/j.ajog.2009.06.060

PY - 2009

Y1 - 2009

N2 - OBJECTIVE: We assessed whether preeclampsia correlates with the long-term postnatal health of the offspring. STUDY DESIGN: We conducted a population-based cohort study of 1,618,481 singletons born in Denmark (1978-2004) with up to 27 years of follow-up. We used Cox regression to estimate the associations between preeclampsia and long-term health outcomes of the offspring. RESULTS: Children born at term exposed to preeclampsia had an increased risk of a variety of diseases, such as endocrine, nutritional, and metabolic diseases (incidence rate ratio, 1.6; 95% confidence interval, 1.5-1.7), and diseases of the blood and blood-forming organs (incidence rate ratio, 1.5; 95% confidence interval, 1.3-1.8). Children born preterm exposed to preeclampsia had a similar pattern of hospitalizations compared with the children born preterm unexposed to preeclampsia, although they had a decreased risk of cerebral palsy (incidence rate ratio, 0.7; 95% confidence interval, 0.6-0.9). CONCLUSION: Preeclampsia was associated with an increased risk of being hospitalized for a number of diseases, especially in the children born at term.

AB - OBJECTIVE: We assessed whether preeclampsia correlates with the long-term postnatal health of the offspring. STUDY DESIGN: We conducted a population-based cohort study of 1,618,481 singletons born in Denmark (1978-2004) with up to 27 years of follow-up. We used Cox regression to estimate the associations between preeclampsia and long-term health outcomes of the offspring. RESULTS: Children born at term exposed to preeclampsia had an increased risk of a variety of diseases, such as endocrine, nutritional, and metabolic diseases (incidence rate ratio, 1.6; 95% confidence interval, 1.5-1.7), and diseases of the blood and blood-forming organs (incidence rate ratio, 1.5; 95% confidence interval, 1.3-1.8). Children born preterm exposed to preeclampsia had a similar pattern of hospitalizations compared with the children born preterm unexposed to preeclampsia, although they had a decreased risk of cerebral palsy (incidence rate ratio, 0.7; 95% confidence interval, 0.6-0.9). CONCLUSION: Preeclampsia was associated with an increased risk of being hospitalized for a number of diseases, especially in the children born at term.

U2 - 10.1016/j.ajog.2009.06.060

DO - 10.1016/j.ajog.2009.06.060

M3 - Journal article

C2 - 19733276

VL - 201

SP - 269.e1-269.e10

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 3

ER -