Højdosis A-vitamin-tilskud saenker børnedødelighed i lavindkomstlande --kan det blive bedre?

Christine Stabell Benn, Birgitte Rode Diness, Ane Baerent Fisker, Dorthe Christoffersen, Henrik Friis

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

Many large intervention trials have shown that high-dose vitamin A supplementation decreases overall childhood mortality rates by 23-30%, making it one of the most cost-effective interventions in low-income countries. However, with regard to morbidity and the immunological mechanisms behind the beneficial effect on mortality rates, the results are less clear. Furthermore, vitamin A seems to be beneficial in some but not all age groups, and smaller doses may be even better than higher doses. It seems likely that by pursuing these inconsistent observations, vitamin A supplementation programmes can be optimised.

Bidragets oversatte titelHigh-dose vitamin A supplementation decreases childhood mortality rates in low-income countries--can the results be improved?
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind168
Udgave nummer25
Sider (fra-til)2442-2445
ISSN0041-5782
StatusUdgivet - 19. jun. 2006
Udgivet eksterntJa

Emneord

  • Child, Preschool
  • Developing Countries
  • Dose-Response Relationship, Drug
  • Humans
  • Immunity, Cellular
  • Infant
  • Infant Mortality
  • Infant, Newborn
  • Infection
  • Poverty
  • Socioeconomic Factors
  • Vitamin A
  • Vitamin A Deficiency

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