Håndtering af amlodipinudløste ankelødemer

Birgit K. Skovbjerg*, Ole Møller-Helgestad, Christina Stolzenburg Oxlund, Bo Christensen, Jakob N Henriksen

*Kontaktforfatter

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstract

Pedal oedema is a well-known adverse effect of amlodipine, but significantly less frequent if only half of the maximum recommended dosage is used. Diuretics are ineffective. To cause as few side effects as possible, options for managing are prioritised in this review: Reduce dosage, switch to lercanidipine/lacidipine, switch to another group, add/increase dosage of an ACE-inhibitor/angiotensin II-receptor blocker, administer at night, or switch to verapamil/diltiazem. Non-pharmacologic actions or observation may be considered when the oedemas are mild and not bothersome.
Bidragets oversatte titelManagement of amlodipine-induced ankle oedema
OriginalsprogDansk
ArtikelnummerV07220460
TidsskriftUgeskrift for Læger
Vol/bind185
Udgave nummer17
Sider (fra-til)1601-1603
ISSN0041-5782
StatusUdgivet - 4. sep. 2023

Emneord

  • Amlodipine/adverse effects
  • Ankle
  • Calcium Channel Blockers/adverse effects
  • Drug-Related Side Effects and Adverse Reactions
  • Edema/drug therapy
  • Humans
  • Hypertension/drug therapy

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