Glucocorticoid gene regulation of aquaporin-7

Laura González-Dávalos, Mariana Álvarez-Pérez, Tania Quesada-López, Rubén Cereijo, Laura Campderrós, Enrique Piña, Armando Shimada, Francesc Villarroya, Alfredo Varela-Echavarria, Ofelia Mora*

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Publikation: Kapitel i bog/rapport/konference-proceedingKapitel i bogForskningpeer review

Abstrakt

AQP7 is the primary glycerol transporter in white (WAT) and brown (BAT) adipose tissues. There are immediate and quantitatively important actions of cortisone over the expression of AQP7 in murine and human adipocytes. Short-term response (minutes) of cortisone treatment result in an mRNA overexpression in white and brown differentiated adipocytes (between 1.5 and 6 folds). Conversely, long-term response (hours or days) result in decreased mRNA expression. The effects observed on AQP7 mRNA expression upon cortisone treatment in brown and white differentiated adipocytes are concordant with those observed for GK and HSD1B11.

OriginalsprogEngelsk
TitelVitamins and Hormones
RedaktørerGerald Litwack
Antal sider29
ForlagAcademic Press
Publikationsdato2020
Sider179-207
ISBN (Trykt)9780128208090
DOI
StatusUdgivet - 2020
NavnVitamins and Hormones
Vol/bind112
ISSN0083-6729

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  • Citationsformater

    González-Dávalos, L., Álvarez-Pérez, M., Quesada-López, T., Cereijo, R., Campderrós, L., Piña, E., Shimada, A., Villarroya, F., Varela-Echavarria, A., & Mora, O. (2020). Glucocorticoid gene regulation of aquaporin-7. I G. Litwack (red.), Vitamins and Hormones (s. 179-207). Academic Press. Vitamins and Hormones, Bind. 112 https://doi.org/10.1016/bs.vh.2019.08.005